Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study
BackgroundSlow walking speed has been shown to predict cognitive decline in older individuals, but studies conducted among Chinese older adults are scarce. We examined the association of walking speed with cognitive function and the trajectory of cognitive decline among Chinese adults aged 60 years...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1003896/full |
| _version_ | 1811232780020875264 |
|---|---|
| author | Jianping Liu Kaiwang Cui Qian Chen Zhiteng Li Jing Fu Xiangwen Gong Hui Xu |
| author_facet | Jianping Liu Kaiwang Cui Qian Chen Zhiteng Li Jing Fu Xiangwen Gong Hui Xu |
| author_sort | Jianping Liu |
| collection | DOAJ |
| description | BackgroundSlow walking speed has been shown to predict cognitive decline in older individuals, but studies conducted among Chinese older adults are scarce. We examined the association of walking speed with cognitive function and the trajectory of cognitive decline among Chinese adults aged 60 years and older.MethodsData was from the China Health and Retirement Longitudinal Study (CHARLS), an ongoing nationally representative prospective cohort study. Walking speed was evaluated over a straight 2.5-meter flat course at baseline and categorized into tertiles (the lowest, middle, and highest). Cognitive function was assessed at each wave in three domains: episodic memory, mental status, and global cognition. Data were analyzed using linear mixed-effects models.ResultsA total of 3,954 older adults (48.6% female; mean age: 67.6 ± 5.55 years) were followed for up to 7 years. Participants with lowest walking speed have poorer episodic memory (β = −0.37; 95% CI: −0.46, −0.28), mental status (β = −0.45; 95% CI: −0.60, −0.29), and global cognition (β = −0.81; 95% CI: −1.03, −0.60) over the follow-up. Compared with the highest tertile of walking speed, the lowest walking speed was associated with a faster decline in episodic memory (β = −0.04; 95% CI: −0.07, −0.02), mental status (β = −0.04; 95% CI: −0.07, −0.01), and global cognition (β = −0.06; 95% CI: −0.11, −0.01).ConclusionSlower walking speed is associated with subsequent risk of poorer cognitive function and faster cognitive decline in older Chinese adults. |
| first_indexed | 2024-04-12T11:10:03Z |
| format | Article |
| id | doaj.art-31b7e9896ec1475e99364e63ef9d7a1f |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-12T11:10:03Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-31b7e9896ec1475e99364e63ef9d7a1f2022-12-22T03:35:39ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-11-011410.3389/fnagi.2022.10038961003896Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort studyJianping Liu0Kaiwang Cui1Qian Chen2Zhiteng Li3Jing Fu4Xiangwen Gong5Hui Xu6Department of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaDepartment of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaDepartment of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaDepartment of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaDepartment of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaDepartment of Respiratory and Critical Care Medicine, Ganzhou Institute of Respiratory Diseases, The Fifth People’s Hospital of Ganzhou, Ganzhou, Jiangxi, ChinaBig Data Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, ChinaBackgroundSlow walking speed has been shown to predict cognitive decline in older individuals, but studies conducted among Chinese older adults are scarce. We examined the association of walking speed with cognitive function and the trajectory of cognitive decline among Chinese adults aged 60 years and older.MethodsData was from the China Health and Retirement Longitudinal Study (CHARLS), an ongoing nationally representative prospective cohort study. Walking speed was evaluated over a straight 2.5-meter flat course at baseline and categorized into tertiles (the lowest, middle, and highest). Cognitive function was assessed at each wave in three domains: episodic memory, mental status, and global cognition. Data were analyzed using linear mixed-effects models.ResultsA total of 3,954 older adults (48.6% female; mean age: 67.6 ± 5.55 years) were followed for up to 7 years. Participants with lowest walking speed have poorer episodic memory (β = −0.37; 95% CI: −0.46, −0.28), mental status (β = −0.45; 95% CI: −0.60, −0.29), and global cognition (β = −0.81; 95% CI: −1.03, −0.60) over the follow-up. Compared with the highest tertile of walking speed, the lowest walking speed was associated with a faster decline in episodic memory (β = −0.04; 95% CI: −0.07, −0.02), mental status (β = −0.04; 95% CI: −0.07, −0.01), and global cognition (β = −0.06; 95% CI: −0.11, −0.01).ConclusionSlower walking speed is associated with subsequent risk of poorer cognitive function and faster cognitive decline in older Chinese adults.https://www.frontiersin.org/articles/10.3389/fnagi.2022.1003896/fullwalking speedcognitive functionolder Chinese adultsnationalcohort study |
| spellingShingle | Jianping Liu Kaiwang Cui Qian Chen Zhiteng Li Jing Fu Xiangwen Gong Hui Xu Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study Frontiers in Aging Neuroscience walking speed cognitive function older Chinese adults national cohort study |
| title | Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study |
| title_full | Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study |
| title_fullStr | Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study |
| title_full_unstemmed | Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study |
| title_short | Association of walking speed with cognitive function in Chinese older adults: A nationally representative cohort study |
| title_sort | association of walking speed with cognitive function in chinese older adults a nationally representative cohort study |
| topic | walking speed cognitive function older Chinese adults national cohort study |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1003896/full |
| work_keys_str_mv | AT jianpingliu associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT kaiwangcui associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT qianchen associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT zhitengli associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT jingfu associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT xiangwengong associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy AT huixu associationofwalkingspeedwithcognitivefunctioninchineseolderadultsanationallyrepresentativecohortstudy |