First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016

We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization showed high similarity to the reference genome NTUH-K...

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Main Authors: C. Pichler, M. Büchsel, J.W. Rossen, M. Vavra, S. Reuter, W.V. Kern, R. Thimme, A. Mischnik
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:New Microbes and New Infections
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297517300197
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author C. Pichler
M. Büchsel
J.W. Rossen
M. Vavra
S. Reuter
W.V. Kern
R. Thimme
A. Mischnik
author_facet C. Pichler
M. Büchsel
J.W. Rossen
M. Vavra
S. Reuter
W.V. Kern
R. Thimme
A. Mischnik
author_sort C. Pichler
collection DOAJ
description We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization showed high similarity to the reference genome NTUH-K2044 isolated in Asia. The isolate was assigned as ST2398 (clonal complex 66). The findings underline global spread of hypervirulent Klebsiella pneumoniae strains to Europe.
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spelling doaj.art-31b86b240be947e98d71bc07a30fbf9e2022-12-21T18:54:55ZengElsevierNew Microbes and New Infections2052-29752017-05-0117C778010.1016/j.nmni.2017.02.006First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016C. Pichler0M. Büchsel1J.W. Rossen2M. Vavra3S. Reuter4W.V. Kern5R. Thimme6A. Mischnik7Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyInstitute for Medical Microbiology and Hygiene, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyDepartment of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsDivision of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyDepartment of Infection Prevention and Hospital Hygiene, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyDivision of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyDepartment of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyDivision of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, GermanyWe report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization showed high similarity to the reference genome NTUH-K2044 isolated in Asia. The isolate was assigned as ST2398 (clonal complex 66). The findings underline global spread of hypervirulent Klebsiella pneumoniae strains to Europe.http://www.sciencedirect.com/science/article/pii/S2052297517300197EndophthalmitishypervirulentKlebsiella pneumoniaeliver abscessST2398
spellingShingle C. Pichler
M. Büchsel
J.W. Rossen
M. Vavra
S. Reuter
W.V. Kern
R. Thimme
A. Mischnik
First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
New Microbes and New Infections
Endophthalmitis
hypervirulent
Klebsiella pneumoniae
liver abscess
ST2398
title First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
title_full First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
title_fullStr First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
title_full_unstemmed First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
title_short First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016
title_sort first report of invasive liver abscess syndrome with endophthalmitis caused by a k2 serotype st2398 hypervirulent klebsiella pneumoniae in germany 2016
topic Endophthalmitis
hypervirulent
Klebsiella pneumoniae
liver abscess
ST2398
url http://www.sciencedirect.com/science/article/pii/S2052297517300197
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