The six-minute step test can predict COPD exacerbations: a 36-month follow-up study
Abstract The six-minute step test (6MST) has been shown to be effective in assessing exercise capacity in individuals with COPD regardless of severity and, despite its easy execution, accessibility and validity, information on the prognostic power of this test remains uncertain. The aim of this stud...
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| Format: | Article |
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Nature Portfolio
2024-02-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-54338-9 |
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| author | Aldair Darlan Santos-de-Araújo Cássia da Luz Goulart Renan Shida Marinho Izadora Moraes Dourado Renata Gonçalves Mendes Meliza Goi Roscani Daniela Bassi-Dibai Shane A. Phillips Ross Arena Audrey Borghi-Silva |
| author_facet | Aldair Darlan Santos-de-Araújo Cássia da Luz Goulart Renan Shida Marinho Izadora Moraes Dourado Renata Gonçalves Mendes Meliza Goi Roscani Daniela Bassi-Dibai Shane A. Phillips Ross Arena Audrey Borghi-Silva |
| author_sort | Aldair Darlan Santos-de-Araújo |
| collection | DOAJ |
| description | Abstract The six-minute step test (6MST) has been shown to be effective in assessing exercise capacity in individuals with COPD regardless of severity and, despite its easy execution, accessibility and validity, information on the prognostic power of this test remains uncertain. The aim of this study is to investigate whether the 6MST can predict the occurrence of exacerbations in patients with COPD. This is a prospective cohort study with a 36-month follow-up in patients with COPD. All patients completed a clinical assessment, followed by pulmonary function testing and a 6MST. The 6MST was performed on a 20 cm high step; heart rate, blood pressure, oxygen saturation, BORG dyspnea and fatigue were collected. Sixty-four patients were included in the study, the majority being elderly men. Performance on the 6MST demonstrated lower performance compared to normative values proposed in the literature, indicating a reduced functional capacity. Kaplan Meier analysis revealed that ≤ 59 steps climbed during the 6MST was a strong predictor of COPD exacerbation over a 36-month follow-up. We have identified a minimal threshold number of steps (≤ 59) obtained through the 6MST may be able predict the risk of exacerbations in patients with COPD. |
| first_indexed | 2024-03-07T15:06:00Z |
| format | Article |
| id | doaj.art-31b915142efb42ddb482da7282322a4b |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-07T15:06:00Z |
| publishDate | 2024-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-31b915142efb42ddb482da7282322a4b2024-03-05T18:53:46ZengNature PortfolioScientific Reports2045-23222024-02-011411910.1038/s41598-024-54338-9The six-minute step test can predict COPD exacerbations: a 36-month follow-up studyAldair Darlan Santos-de-Araújo0Cássia da Luz Goulart1Renan Shida Marinho2Izadora Moraes Dourado3Renata Gonçalves Mendes4Meliza Goi Roscani5Daniela Bassi-Dibai6Shane A. Phillips7Ross Arena8Audrey Borghi-Silva9Cardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosDepartment of Medicine, Universidade Federal de São Carlos (UFSCar)Postgraduate Program in Management in Health Programs and Services, Universidade CEUMADepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois ChicagoDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois ChicagoCardiopulmonary Physiotherapy Laboratory, Universidade Federal de São CarlosAbstract The six-minute step test (6MST) has been shown to be effective in assessing exercise capacity in individuals with COPD regardless of severity and, despite its easy execution, accessibility and validity, information on the prognostic power of this test remains uncertain. The aim of this study is to investigate whether the 6MST can predict the occurrence of exacerbations in patients with COPD. This is a prospective cohort study with a 36-month follow-up in patients with COPD. All patients completed a clinical assessment, followed by pulmonary function testing and a 6MST. The 6MST was performed on a 20 cm high step; heart rate, blood pressure, oxygen saturation, BORG dyspnea and fatigue were collected. Sixty-four patients were included in the study, the majority being elderly men. Performance on the 6MST demonstrated lower performance compared to normative values proposed in the literature, indicating a reduced functional capacity. Kaplan Meier analysis revealed that ≤ 59 steps climbed during the 6MST was a strong predictor of COPD exacerbation over a 36-month follow-up. We have identified a minimal threshold number of steps (≤ 59) obtained through the 6MST may be able predict the risk of exacerbations in patients with COPD.https://doi.org/10.1038/s41598-024-54338-9Chronic obstructive pulmonary diseaseFunctional capacitySix-minute step testExacerbation |
| spellingShingle | Aldair Darlan Santos-de-Araújo Cássia da Luz Goulart Renan Shida Marinho Izadora Moraes Dourado Renata Gonçalves Mendes Meliza Goi Roscani Daniela Bassi-Dibai Shane A. Phillips Ross Arena Audrey Borghi-Silva The six-minute step test can predict COPD exacerbations: a 36-month follow-up study Scientific Reports Chronic obstructive pulmonary disease Functional capacity Six-minute step test Exacerbation |
| title | The six-minute step test can predict COPD exacerbations: a 36-month follow-up study |
| title_full | The six-minute step test can predict COPD exacerbations: a 36-month follow-up study |
| title_fullStr | The six-minute step test can predict COPD exacerbations: a 36-month follow-up study |
| title_full_unstemmed | The six-minute step test can predict COPD exacerbations: a 36-month follow-up study |
| title_short | The six-minute step test can predict COPD exacerbations: a 36-month follow-up study |
| title_sort | six minute step test can predict copd exacerbations a 36 month follow up study |
| topic | Chronic obstructive pulmonary disease Functional capacity Six-minute step test Exacerbation |
| url | https://doi.org/10.1038/s41598-024-54338-9 |
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