New Targeted Therapy for Non-Small Cell Lung Cancer

Lung cancer ranks first in cancer mortality in Korea and cancer incidence in Korean men. More than half of Korean lung cancer patients undergo chemotherapy, including adjuvant therapy. Cytotoxic agents, targeted therapy, and immune checkpoint inhibitors are used in chemotherapy according to the biop...

Full description

Bibliographic Details
Main Authors: Eun Ki Chung, Seung Hyun Yong, Eun Hye Lee, Eun Young Kim, Yoon Soo Chang, Sang Hoon Lee
Format: Article
Language:English
Published: The Korean Academy of Tuberculosis and Respiratory Diseases 2023-01-01
Series:Tuberculosis and Respiratory Diseases
Subjects:
Online Access:http://e-trd.org/upload/pdf/trd-2022-0066.pdf
_version_ 1797962707280855040
author Eun Ki Chung
Seung Hyun Yong
Eun Hye Lee
Eun Young Kim
Yoon Soo Chang
Sang Hoon Lee
author_facet Eun Ki Chung
Seung Hyun Yong
Eun Hye Lee
Eun Young Kim
Yoon Soo Chang
Sang Hoon Lee
author_sort Eun Ki Chung
collection DOAJ
description Lung cancer ranks first in cancer mortality in Korea and cancer incidence in Korean men. More than half of Korean lung cancer patients undergo chemotherapy, including adjuvant therapy. Cytotoxic agents, targeted therapy, and immune checkpoint inhibitors are used in chemotherapy according to the biopsy and genetic test results. Among chemotherapy, the one that has developed rapidly is targeted therapy. The National Comprehensive Cancer Network (NCCN) guidelines have been updated recently for targeted therapy of multiple gene mutations, and targeted therapy is used not only for chemotherapy but also for adjuvant therapy. While previously targeted therapies have been developed for common genetic mutations, recently targeted therapies have been developed to overcome uncommon mutations or drug resistance that have occurred since previous targeted therapy. Therefore, this study describes recent, rapidly developing targeted therapies.
first_indexed 2024-04-11T01:17:06Z
format Article
id doaj.art-31bda94a476c41b3ad82f53187f29baa
institution Directory Open Access Journal
issn 1738-3536
2005-6184
language English
last_indexed 2024-04-11T01:17:06Z
publishDate 2023-01-01
publisher The Korean Academy of Tuberculosis and Respiratory Diseases
record_format Article
series Tuberculosis and Respiratory Diseases
spelling doaj.art-31bda94a476c41b3ad82f53187f29baa2023-01-03T23:11:59ZengThe Korean Academy of Tuberculosis and Respiratory DiseasesTuberculosis and Respiratory Diseases1738-35362005-61842023-01-0186111310.4046/trd.2022.00664798New Targeted Therapy for Non-Small Cell Lung CancerEun Ki Chung0Seung Hyun Yong1Eun Hye Lee2Eun Young Kim3Yoon Soo Chang4Sang Hoon Lee Division of Pulmonary, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea Division of Pulmonary, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea Division of Pulmonary, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea Division of Pulmonary, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea Division of Pulmonary, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of KoreaLung cancer ranks first in cancer mortality in Korea and cancer incidence in Korean men. More than half of Korean lung cancer patients undergo chemotherapy, including adjuvant therapy. Cytotoxic agents, targeted therapy, and immune checkpoint inhibitors are used in chemotherapy according to the biopsy and genetic test results. Among chemotherapy, the one that has developed rapidly is targeted therapy. The National Comprehensive Cancer Network (NCCN) guidelines have been updated recently for targeted therapy of multiple gene mutations, and targeted therapy is used not only for chemotherapy but also for adjuvant therapy. While previously targeted therapies have been developed for common genetic mutations, recently targeted therapies have been developed to overcome uncommon mutations or drug resistance that have occurred since previous targeted therapy. Therefore, this study describes recent, rapidly developing targeted therapies.http://e-trd.org/upload/pdf/trd-2022-0066.pdfcarcinoma, non-small-cell lungmolecular targeted therapyprognosis
spellingShingle Eun Ki Chung
Seung Hyun Yong
Eun Hye Lee
Eun Young Kim
Yoon Soo Chang
Sang Hoon Lee
New Targeted Therapy for Non-Small Cell Lung Cancer
Tuberculosis and Respiratory Diseases
carcinoma, non-small-cell lung
molecular targeted therapy
prognosis
title New Targeted Therapy for Non-Small Cell Lung Cancer
title_full New Targeted Therapy for Non-Small Cell Lung Cancer
title_fullStr New Targeted Therapy for Non-Small Cell Lung Cancer
title_full_unstemmed New Targeted Therapy for Non-Small Cell Lung Cancer
title_short New Targeted Therapy for Non-Small Cell Lung Cancer
title_sort new targeted therapy for non small cell lung cancer
topic carcinoma, non-small-cell lung
molecular targeted therapy
prognosis
url http://e-trd.org/upload/pdf/trd-2022-0066.pdf
work_keys_str_mv AT eunkichung newtargetedtherapyfornonsmallcelllungcancer
AT seunghyunyong newtargetedtherapyfornonsmallcelllungcancer
AT eunhyelee newtargetedtherapyfornonsmallcelllungcancer
AT eunyoungkim newtargetedtherapyfornonsmallcelllungcancer
AT yoonsoochang newtargetedtherapyfornonsmallcelllungcancer
AT sanghoonlee newtargetedtherapyfornonsmallcelllungcancer