Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1

Background/purpose: Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Recent data suggest that a subpopulation of cancer cells, termed cancer stem cells (CSCs), is capable of initiating, maintaining, and expanding the growth of tumors. Importantly, CSCs confer chemo- and radioresi...

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Bibliographic Details
Main Authors: Lo-Lin Tsai, Cheng-Chia Yu, Jeng-Fan Lo, Wen-Wei Sung, Huei Lee, Shiow-Ling Chen, Ming-Yung Chou
Format: Article
Language:English
Published: Elsevier 2012-06-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790212000384