Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial
Background: Despite the decreasing rate of under nutrition children in recent years overall, the negative affect in growth and development make it as a main concern in the world. Applying an available and appropriate supplementary food is a major approach in treating children with Moderate Acute M...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Electronic Physician
2017-12-01
|
Series: | Electronic Physician |
Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843437/ |
_version_ | 1818484063798820864 |
---|---|
author | Roghayeh Javan Akram Kooshki, Monavvar Afzalaghaee Mitra Aldaghi Mahdi Yousefi |
author_facet | Roghayeh Javan Akram Kooshki, Monavvar Afzalaghaee Mitra Aldaghi Mahdi Yousefi |
author_sort | Roghayeh Javan |
collection | DOAJ |
description | Background: Despite the decreasing rate of under nutrition children in recent years overall, the negative affect in
growth and development make it as a main concern in the world. Applying an available and appropriate
supplementary food is a major approach in treating children with Moderate Acute Malnutrition (MAM).
Objective: To compare the effectiveness of a new supplementary blended flour (containing chickpea, rice, wheat
and barley, named Shadameen) in combination with multivitamin/mineral supplement and nutritional counseling
versus multivitamin/mineral supplement and nutritional counseling alone, in the treatment of children with
MAM.
Methods: This randomized controlled trial study was conducted at Heshmatiyeh Hospital in Sabzevar city in
Iran, from January 2016 to December 2016. Seventy infants, aged 9 to 24 months with MAM who were referred
from urban health centers to the hospital clinic were included. They were randomly assigned to receive, for about
3 months, either multivitamin / mineral supplement and nutritional counseling alone or in combination with an
extra supplementary blended food. We analyzed weight, length, weight for length Z score (WLZ), weight for age
Z score (WAZ) and length for weight Z score (LAZ), along with recovery rate and adverse events among the two
groups. The data were analyzed using SPSS version 16. We used statistics, Chi-square, independent t-test, and
Fisher's exact test for the analyses of primary and secondary outcomes.
Results: The food supplementation infant's mean weight and WLZ and WAZ were greater compared with the
other group (0.81±0.29 gr and 0.55±0.33 gr, p=0.002), (0.36±0.36 and 0.02±0.52, p=0.003), (0.40±0.33 and
0.09±0.37, p=0.001). The recovery rate in the food supplemented group was significantly higher than the other
group (68.4%, 31.6%, p=0.001). No adverse reactions were observed. There were no significant differences in
LAZ at the end of the study between the two groups (p=0.53).
Conclusion: This study showed that Shadameen in combination with multivitamin/mineral and counselling
therapy can be more effective in decreasing the wasting rate of children with MAM than vitamin/mineral and
Electronic physician
Page 6079
counseling therapy alone.
Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the
Irct ID: IRCT2015040921670N1.
Funding: This study was financially supported by the vice chancellor for research office, Mashhad University of
Medical Sciences. |
first_indexed | 2024-12-10T15:50:26Z |
format | Article |
id | doaj.art-31c55f258e5f408caf22aefd62b27ec7 |
institution | Directory Open Access Journal |
issn | 2008-5842 2008-5842 |
language | English |
last_indexed | 2024-12-10T15:50:26Z |
publishDate | 2017-12-01 |
publisher | Electronic Physician |
record_format | Article |
series | Electronic Physician |
spelling | doaj.art-31c55f258e5f408caf22aefd62b27ec72022-12-22T01:42:49ZengElectronic PhysicianElectronic Physician2008-58422008-58422017-12-019126078608610.19082/6078Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trialRoghayeh JavanAkram Kooshki,Monavvar AfzalaghaeeMitra AldaghiMahdi YousefiBackground: Despite the decreasing rate of under nutrition children in recent years overall, the negative affect in growth and development make it as a main concern in the world. Applying an available and appropriate supplementary food is a major approach in treating children with Moderate Acute Malnutrition (MAM). Objective: To compare the effectiveness of a new supplementary blended flour (containing chickpea, rice, wheat and barley, named Shadameen) in combination with multivitamin/mineral supplement and nutritional counseling versus multivitamin/mineral supplement and nutritional counseling alone, in the treatment of children with MAM. Methods: This randomized controlled trial study was conducted at Heshmatiyeh Hospital in Sabzevar city in Iran, from January 2016 to December 2016. Seventy infants, aged 9 to 24 months with MAM who were referred from urban health centers to the hospital clinic were included. They were randomly assigned to receive, for about 3 months, either multivitamin / mineral supplement and nutritional counseling alone or in combination with an extra supplementary blended food. We analyzed weight, length, weight for length Z score (WLZ), weight for age Z score (WAZ) and length for weight Z score (LAZ), along with recovery rate and adverse events among the two groups. The data were analyzed using SPSS version 16. We used statistics, Chi-square, independent t-test, and Fisher's exact test for the analyses of primary and secondary outcomes. Results: The food supplementation infant's mean weight and WLZ and WAZ were greater compared with the other group (0.81±0.29 gr and 0.55±0.33 gr, p=0.002), (0.36±0.36 and 0.02±0.52, p=0.003), (0.40±0.33 and 0.09±0.37, p=0.001). The recovery rate in the food supplemented group was significantly higher than the other group (68.4%, 31.6%, p=0.001). No adverse reactions were observed. There were no significant differences in LAZ at the end of the study between the two groups (p=0.53). Conclusion: This study showed that Shadameen in combination with multivitamin/mineral and counselling therapy can be more effective in decreasing the wasting rate of children with MAM than vitamin/mineral and Electronic physician Page 6079 counseling therapy alone. Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT2015040921670N1. Funding: This study was financially supported by the vice chancellor for research office, Mashhad University of Medical Sciences.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843437/MalnutritionChildrenSupplementary foodChickpea |
spellingShingle | Roghayeh Javan Akram Kooshki, Monavvar Afzalaghaee Mitra Aldaghi Mahdi Yousefi Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial Electronic Physician Malnutrition Children Supplementary food Chickpea |
title | Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial |
title_full | Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial |
title_fullStr | Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial |
title_full_unstemmed | Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial |
title_short | Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial |
title_sort | effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in iran a randomized clinical trial |
topic | Malnutrition Children Supplementary food Chickpea |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843437/ |
work_keys_str_mv | AT roghayehjavan effectivenessofsupplementaryblendedflourbasedonchickpeaandcerealsforthetreatmentofinfantswithmoderateacutemalnutritioniniranarandomizedclinicaltrial AT akramkooshki effectivenessofsupplementaryblendedflourbasedonchickpeaandcerealsforthetreatmentofinfantswithmoderateacutemalnutritioniniranarandomizedclinicaltrial AT monavvarafzalaghaee effectivenessofsupplementaryblendedflourbasedonchickpeaandcerealsforthetreatmentofinfantswithmoderateacutemalnutritioniniranarandomizedclinicaltrial AT mitraaldaghi effectivenessofsupplementaryblendedflourbasedonchickpeaandcerealsforthetreatmentofinfantswithmoderateacutemalnutritioniniranarandomizedclinicaltrial AT mahdiyousefi effectivenessofsupplementaryblendedflourbasedonchickpeaandcerealsforthetreatmentofinfantswithmoderateacutemalnutritioniniranarandomizedclinicaltrial |