Engineering defected 2D Pd/H-TiO2 nanosonosensitizers for hypoxia alleviation and enhanced sono-chemodynamic cancer nanotherapy

Engineering defected 2D Pd/H-TiO2 nanosonosensitizers for hypoxia alleviation and enhanced sono-chemodynamic cancer nanotherapy

Abstract Background Sonodynamic therapy (SDT) is a burgeoning modality for cancer therapy owing to its high tissue-penetrating capability, controllability and safety. Whereas, the undesirable reactive oxygen species (ROS) yield of sonosensitizers and tumor hypoxia are two vulnerable spots of SDT. Th...

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Bibliographic Details
Main Authors: Xiaohui Qiao, Liyun Xue, Hui Huang, Xinyue Dai, Yu Chen, Hong Ding
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Nanobiotechnology
Subjects:
Chemodynamic therapy
Nanozyme
Oxygen deficiency
Pd/H-TiO2 nanosheets
Sonodynamic therapy
Online Access:https://doi.org/10.1186/s12951-022-01398-6

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