An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety
Melissa officinalis L. is a plant of the Lamiaceae family known in numerous countries for its medicinal activities. This plant has been used since ancient times to treat different disorders, including gastrointestinal, cardiovascular, neurological, psychological conditions. M. officinalis contains s...
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| Format: | Article |
| Language: | English |
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IMR Press
2022-06-01
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| Series: | Frontiers in Bioscience-Scholar |
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| Online Access: | https://www.imrpress.com/journal/FBS/14/2/10.31083/j.fbs1402016 |
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| author | Wissam Zam Cristina Quispe Javad Sharifi-Rad María Dolores López Mauricio Schoebitz Miquel Martorell Farukh Sharopov Patrick Valere Tsouh Fokou Abhay Prakash Mishra Deepak Chandran Manoj Kumar Jen-Tsung Chen Raffaele Pezzani |
| author_facet | Wissam Zam Cristina Quispe Javad Sharifi-Rad María Dolores López Mauricio Schoebitz Miquel Martorell Farukh Sharopov Patrick Valere Tsouh Fokou Abhay Prakash Mishra Deepak Chandran Manoj Kumar Jen-Tsung Chen Raffaele Pezzani |
| author_sort | Wissam Zam |
| collection | DOAJ |
| description | Melissa officinalis L. is a plant of the Lamiaceae family known in numerous countries for its medicinal activities. This plant has been used since ancient times to treat different disorders, including gastrointestinal, cardiovascular, neurological, psychological conditions. M. officinalis contains several phytochemicals such as phenolic acids, flavonoids, terpenoids, and many others at the basis of its pharmacological activities. Indeed, the plant can have antioxidant, anti-inflammatory, antispasmodic, antimicrobial, neuroprotective, nephroprotective, antinociceptive effects. Given its consolidated use, M. officinalis has also been experimented with clinical settings, demonstrating interesting properties against different human diseases, such as anxiety, sleeping difficulties, palpitation, hypertension, depression, dementia, infantile colic, bruxism, metabolic problems, Alzheimer’s disease, and sexual disorders. As for any natural compound, drug, or plant extract, also M. officinalis can have adverse effects, even though the reported events are very rare and the plant can be considered substantially safe. This review has been prepared with a specific research strategy, interrogating different databases with the keyword M. officinalis. Moreover, this work analyzes the properties of this plant updating currently available literature, with a special emphasis on human studies. |
| first_indexed | 2024-12-12T15:33:05Z |
| format | Article |
| id | doaj.art-31c5c2377d1443c1bffecc0b1e25c68e |
| institution | Directory Open Access Journal |
| issn | 1945-0516 |
| language | English |
| last_indexed | 2024-12-12T15:33:05Z |
| publishDate | 2022-06-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Frontiers in Bioscience-Scholar |
| spelling | doaj.art-31c5c2377d1443c1bffecc0b1e25c68e2022-12-22T00:20:05ZengIMR PressFrontiers in Bioscience-Scholar1945-05162022-06-011421610.31083/j.fbs1402016S1945-0516(22)00065-XAn Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxietyWissam Zam0Cristina Quispe1Javad Sharifi-Rad2María Dolores López3Mauricio Schoebitz4Miquel Martorell5Farukh Sharopov6Patrick Valere Tsouh Fokou7Abhay Prakash Mishra8Deepak Chandran9Manoj Kumar10Jen-Tsung Chen11Raffaele Pezzani12Department of Analytical and Food Chemistry, Faculty of Pharmacy, Al-Andalus University for Medical Sciences, 35XQ+C2F Tartous, SyriaFacultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, 1110939 Iquique, ChileFacultad de Medicina, Universidad del Azuay, 14-008 Cuenca, EcuadorDepartment of Plant Production, Faculty of Agronomy, Universidad de Concepción, Avenida Vicente Mendez, 595, 3812120 Chillán, ChileDepartamento de Suelos y Recursos Naturales, Facultad de Agronomía, Universidad de Concepción, 4070386 Concepción, ChileDepartment of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, 4070386 Concepción, ChileResearch Institution “Chinese-Tajik Innovation Center for Natural Products” of the National Academy of Sciences of Tajikistan, Ayni str. 299/2, 734063 Dushanbe, TajikistanFaculty of Science, University of Bamenda, 39 Bamenda-Bambili, CameroonDepartment of Pharmacology, University of Free State, 9300 Bloemfontein, South AfricaDepartment of Veterinary Sciences and Animal Husbandry, Amrita School of Agricultural Sciences, Amrita Vishwa Vidyapeetham University, Coimbatore, 642109 Tamil Nadu, IndiaChemical and Biochemical Processing Division, ICAR – Central Institute for Research on Cotton Technology, 400019 Mumbai, IndiaDepartment of Life Sciences, National University of Kaohsiung, 811 Kaohsiung, TaiwanPhytotherapy Lab (PhT-Lab), Endocrinology Unit, Department of Medicine (DIMED), University of Padova, via Ospedale 105, 35128 Padova, ItalyMelissa officinalis L. is a plant of the Lamiaceae family known in numerous countries for its medicinal activities. This plant has been used since ancient times to treat different disorders, including gastrointestinal, cardiovascular, neurological, psychological conditions. M. officinalis contains several phytochemicals such as phenolic acids, flavonoids, terpenoids, and many others at the basis of its pharmacological activities. Indeed, the plant can have antioxidant, anti-inflammatory, antispasmodic, antimicrobial, neuroprotective, nephroprotective, antinociceptive effects. Given its consolidated use, M. officinalis has also been experimented with clinical settings, demonstrating interesting properties against different human diseases, such as anxiety, sleeping difficulties, palpitation, hypertension, depression, dementia, infantile colic, bruxism, metabolic problems, Alzheimer’s disease, and sexual disorders. As for any natural compound, drug, or plant extract, also M. officinalis can have adverse effects, even though the reported events are very rare and the plant can be considered substantially safe. This review has been prepared with a specific research strategy, interrogating different databases with the keyword M. officinalis. Moreover, this work analyzes the properties of this plant updating currently available literature, with a special emphasis on human studies.https://www.imrpress.com/journal/FBS/14/2/10.31083/j.fbs1402016melissa officinalis l.lemon balmphytotherapyphytochemicalshealth propertiesclinical trials |
| spellingShingle | Wissam Zam Cristina Quispe Javad Sharifi-Rad María Dolores López Mauricio Schoebitz Miquel Martorell Farukh Sharopov Patrick Valere Tsouh Fokou Abhay Prakash Mishra Deepak Chandran Manoj Kumar Jen-Tsung Chen Raffaele Pezzani An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety Frontiers in Bioscience-Scholar melissa officinalis l. lemon balm phytotherapy phytochemicals health properties clinical trials |
| title | An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety |
| title_full | An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety |
| title_fullStr | An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety |
| title_full_unstemmed | An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety |
| title_short | An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety |
| title_sort | updated review on the properties of melissa officinalis l not exclusively anti anxiety |
| topic | melissa officinalis l. lemon balm phytotherapy phytochemicals health properties clinical trials |
| url | https://www.imrpress.com/journal/FBS/14/2/10.31083/j.fbs1402016 |
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