Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction
Extrahepatic bile duct obstruction can be caused by various pathologies, most of them being malignant. Painless, progressive jaundice is the usual mode of presentation. We report a case of distal Common Bile Duct (CBD) obstruction due to a Benign Intramural Beale gland hyperplasia mimicking a peri...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/10157/26242_CE(RA1)_F(T)_PF1(RU_VT_RB)%20_PFA(RB_SS).pdf |
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| author | Durairaj Segamalai Anand Lakshmanan Abdul Rehman Abdul Jameel Sofiya Chandrabapulu Kannan Devy Gounder |
| author_facet | Durairaj Segamalai Anand Lakshmanan Abdul Rehman Abdul Jameel Sofiya Chandrabapulu Kannan Devy Gounder |
| author_sort | Durairaj Segamalai |
| collection | DOAJ |
| description | Extrahepatic bile duct obstruction can be caused by various pathologies, most of them being malignant. Painless, progressive
jaundice is the usual mode of presentation. We report a case of distal Common Bile Duct (CBD) obstruction due to a Benign Intramural
Beale gland hyperplasia mimicking a periampullary carcinoma. Peribiliary glands (Beale Glands) are a group of seromucinous
glands, normally seen within the fibromuscular wall and periductal connective tissue in the extrahepatic and large intrahepatic
ducts and also in the neck of the Gall bladder. These glands drain into the bile duct lumen through small channels referred to as
sacculi of Beale. Intramural Beale ducts are lobular aggregates of mucous glands that lie within the wall of the bile duct. Beale
Gland hyperplasia is uncommon, and is rarely large enough to be visible macroscopically or with imaging as an incidental finding.
There are no case reports of this rare entity. It is distinguished from well differentiated bile duct adenocarcinoma by the preservation
of the lobular architecture, lack of cytological atypia and lack of perineural invasion. This case is reported for its rarity. |
| first_indexed | 2024-12-19T10:11:03Z |
| format | Article |
| id | doaj.art-31c73eff950f4f259644c9997fdc32a3 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-19T10:11:03Z |
| publishDate | 2017-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-31c73eff950f4f259644c9997fdc32a32022-12-21T20:26:21ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-07-01117ED10ED1110.7860/JCDR/2017/26242.10157Benign Beale Gland Hyperplasia Mimicking Malignant Biliary ObstructionDurairaj Segamalai0Anand Lakshmanan1Abdul Rehman Abdul Jameel2Sofiya Chandrabapulu3Kannan Devy Gounder4Postgraduate, Institute of surgical gastroenterology, Madras Medical College, Chennai, Tamil Nadu, India.Professor, Institute of surgical gastroenterology, Madras Medical College, Chennait, Tamil Nadu, India.Postgraduate, Institute of surgical gastroenterology, Madras Medical College, Chennai, Tamil Nadu, India. Postgraduate, Institute of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.Professor, Institute of surgical gastroenterology, Madras Medical College, Chennai, Tamil Nadu, India.Extrahepatic bile duct obstruction can be caused by various pathologies, most of them being malignant. Painless, progressive jaundice is the usual mode of presentation. We report a case of distal Common Bile Duct (CBD) obstruction due to a Benign Intramural Beale gland hyperplasia mimicking a periampullary carcinoma. Peribiliary glands (Beale Glands) are a group of seromucinous glands, normally seen within the fibromuscular wall and periductal connective tissue in the extrahepatic and large intrahepatic ducts and also in the neck of the Gall bladder. These glands drain into the bile duct lumen through small channels referred to as sacculi of Beale. Intramural Beale ducts are lobular aggregates of mucous glands that lie within the wall of the bile duct. Beale Gland hyperplasia is uncommon, and is rarely large enough to be visible macroscopically or with imaging as an incidental finding. There are no case reports of this rare entity. It is distinguished from well differentiated bile duct adenocarcinoma by the preservation of the lobular architecture, lack of cytological atypia and lack of perineural invasion. This case is reported for its rarity.https://jcdr.net/articles/PDF/10157/26242_CE(RA1)_F(T)_PF1(RU_VT_RB)%20_PFA(RB_SS).pdflobularobstructive jaundiceperibiliary gland |
| spellingShingle | Durairaj Segamalai Anand Lakshmanan Abdul Rehman Abdul Jameel Sofiya Chandrabapulu Kannan Devy Gounder Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction Journal of Clinical and Diagnostic Research lobular obstructive jaundice peribiliary gland |
| title | Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction |
| title_full | Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction |
| title_fullStr | Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction |
| title_full_unstemmed | Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction |
| title_short | Benign Beale Gland Hyperplasia Mimicking Malignant Biliary Obstruction |
| title_sort | benign beale gland hyperplasia mimicking malignant biliary obstruction |
| topic | lobular obstructive jaundice peribiliary gland |
| url | https://jcdr.net/articles/PDF/10157/26242_CE(RA1)_F(T)_PF1(RU_VT_RB)%20_PFA(RB_SS).pdf |
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