Extracellular matrix in multicellular aggregates acts as a pressure sensor controlling cell proliferation and motility

Imposed deformations play an important role in morphogenesis and tissue homeostasis, both in normal and pathological conditions. To perceive mechanical perturbations of different types and magnitudes, tissues need appropriate detectors, with a compliance that matches the perturbation amplitude. By c...

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Bibliographic Details
Main Authors: Monika E Dolega, Sylvain Monnier, Benjamin Brunel, Jean-François Joanny, Pierre Recho, Giovanni Cappello
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63258

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