Expert consensus on clinical applications of high-frequency oscillations in epilepsy
Abstract Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis. This conse...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-06-01
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| Series: | Acta Epileptologica |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s42494-020-00018-w |
| _version_ | 1818262180537040896 |
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| author | Yuping Wang Dong Zhou Xiaofeng Yang Xin Xu Liankun Ren Tao Yu Wenjing Zhou Xiaoqiu Shao Zhixian Yang Shuang Wang Dezhi Cao Chunyan Liu Shang Yeong Kwan Jing Xiang |
| author_facet | Yuping Wang Dong Zhou Xiaofeng Yang Xin Xu Liankun Ren Tao Yu Wenjing Zhou Xiaoqiu Shao Zhixian Yang Shuang Wang Dezhi Cao Chunyan Liu Shang Yeong Kwan Jing Xiang |
| author_sort | Yuping Wang |
| collection | DOAJ |
| description | Abstract Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis. This consensus includes the definition and standard detection techniques of HFOs, the localizing value of pathological HFOs for epileptic foci, and different ways to distinguish physiological from epileptic HFOs. The latest clinical applications of HFOs in epilepsy and the related findings are also discussed. HFOs will advance our understanding of the pathophysiology of epilepsy. |
| first_indexed | 2024-12-12T18:59:02Z |
| format | Article |
| id | doaj.art-31d357ada6d643138d07a5738aa547b0 |
| institution | Directory Open Access Journal |
| issn | 2524-4434 |
| language | English |
| last_indexed | 2024-12-12T18:59:02Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Epileptologica |
| spelling | doaj.art-31d357ada6d643138d07a5738aa547b02022-12-22T00:15:08ZengBMCActa Epileptologica2524-44342020-06-012111010.1186/s42494-020-00018-wExpert consensus on clinical applications of high-frequency oscillations in epilepsyYuping Wang0Dong Zhou1Xiaofeng Yang2Xin Xu3Liankun Ren4Tao Yu5Wenjing Zhou6Xiaoqiu Shao7Zhixian Yang8Shuang Wang9Dezhi Cao10Chunyan Liu11Shang Yeong Kwan12Jing Xiang13Department of Neurology, Xuanwu Hospital, Capital Medical UniversityDepartment of Neurology, West China Hospital, Sichuan UniversityCenter of Epilepsy, Beijing Institute of Brain Disorders, Capital Medical UniversityDepartment of Neurosurgery, General Hospital of PLADepartment of Neurology, Xuanwu Hospital, Capital Medical UniversityBeijing Key Laboratory of NeuromodulationEpilepsy Center, Tsinghua University Yuquan HospitalDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical UniversityDepartment of Pediatrics, Peking University First HospitalEpilepsy Center, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Neurology, Shenzhen Children’s HospitalDepartment of Neurology, Xuanwu Hospital, Capital Medical UniversitySection of Epilepsy, Neurological Institute, Taipei Veterans General HospitalMEG Center, Cincinnati Children’s Hospital Medical CenterAbstract Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis. This consensus includes the definition and standard detection techniques of HFOs, the localizing value of pathological HFOs for epileptic foci, and different ways to distinguish physiological from epileptic HFOs. The latest clinical applications of HFOs in epilepsy and the related findings are also discussed. HFOs will advance our understanding of the pathophysiology of epilepsy.http://link.springer.com/article/10.1186/s42494-020-00018-wHigh-frequency oscillationsRippleFast rippleInterictal spikeEpilepsyBiomarker |
| spellingShingle | Yuping Wang Dong Zhou Xiaofeng Yang Xin Xu Liankun Ren Tao Yu Wenjing Zhou Xiaoqiu Shao Zhixian Yang Shuang Wang Dezhi Cao Chunyan Liu Shang Yeong Kwan Jing Xiang Expert consensus on clinical applications of high-frequency oscillations in epilepsy Acta Epileptologica High-frequency oscillations Ripple Fast ripple Interictal spike Epilepsy Biomarker |
| title | Expert consensus on clinical applications of high-frequency oscillations in epilepsy |
| title_full | Expert consensus on clinical applications of high-frequency oscillations in epilepsy |
| title_fullStr | Expert consensus on clinical applications of high-frequency oscillations in epilepsy |
| title_full_unstemmed | Expert consensus on clinical applications of high-frequency oscillations in epilepsy |
| title_short | Expert consensus on clinical applications of high-frequency oscillations in epilepsy |
| title_sort | expert consensus on clinical applications of high frequency oscillations in epilepsy |
| topic | High-frequency oscillations Ripple Fast ripple Interictal spike Epilepsy Biomarker |
| url | http://link.springer.com/article/10.1186/s42494-020-00018-w |
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