A critical analysis of Atoh7 (Math5) mRNA splicing in the developing mouse retina.

A critical analysis of Atoh7 (Math5) mRNA splicing in the developing mouse retina.

The Math5 (Atoh7) gene is transiently expressed during retinogenesis by progenitors exiting mitosis, and is essential for ganglion cell (RGC) development. Math5 contains a single exon, and its 1.7 kb mRNA encodes a 149-aa polypeptide. Mouse Math5 mutants have essentially no RGCs or optic nerves. Giv...

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Bibliographic Details
Main Authors:	Lev Prasov, Nadean L Brown, Tom Glaser
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-08-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2927423?pdf=render

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