Microfluidic technology and simulation models in studying pharmacokinetics during pregnancy

Microfluidic technology and simulation models in studying pharmacokinetics during pregnancy

Introduction: Preterm birth rates and maternal and neonatal mortality remain concerning global health issues, necessitating improved strategies for testing therapeutic compounds during pregnancy. Current 2D or 3D cell models and animal models often fail to provide data that can effectively translate...

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Bibliographic Details
Main Authors:	Ananth K. Kammala, Lauren S. Richardson, Enkhtuya Radnaa, Arum Han, Ramkumar Menon
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Series:	Frontiers in Pharmacology
Subjects:	organ on chip simulation model drug transportation and pregnancy pharmacokinetics PBPK pregnancy modeling pregnancy pharmacokinetics by microfluidics simulation
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1241815/full

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