Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence?
Neurofibromatosis I (NF I), an autosomal dominant disorder is associated with increased risk of benign and malignant peripheral nerve sheath tumors and central nervous system tumors. There are only few case reports of breast carcinoma in known patients of NF I. We report a case of basal like carcino...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=2;spage=166;epage=168;aulast=Jinkala |
| _version_ | 1811217499539111936 |
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| author | Sree Rekha Jinkala Nachiappa Ganesh Rajesh Arvind Ramkumar |
| author_facet | Sree Rekha Jinkala Nachiappa Ganesh Rajesh Arvind Ramkumar |
| author_sort | Sree Rekha Jinkala |
| collection | DOAJ |
| description | Neurofibromatosis I (NF I), an autosomal dominant disorder is associated with increased risk of benign and malignant peripheral nerve sheath tumors and central nervous system tumors. There are only few case reports of breast carcinoma in known patients of NF I. We report a case of basal like carcinoma of the breast in a 69-year-old lady who had NF I. Considering the rare association of carcinomas with NF I and finding that both the NF I gene and a breast cancer pre-disposition gene, BRCA 1 are located in close proximity on chromosome 17q makes the association of these two conditions intriguing. |
| first_indexed | 2024-04-12T06:55:49Z |
| format | Article |
| id | doaj.art-31e87eccf04241bba8b38f78c03de055 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-04-12T06:55:49Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-31e87eccf04241bba8b38f78c03de0552022-12-22T03:43:10ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292013-01-0156216616810.4103/0377-4929.118682Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence?Sree Rekha JinkalaNachiappa Ganesh RajeshArvind RamkumarNeurofibromatosis I (NF I), an autosomal dominant disorder is associated with increased risk of benign and malignant peripheral nerve sheath tumors and central nervous system tumors. There are only few case reports of breast carcinoma in known patients of NF I. We report a case of basal like carcinoma of the breast in a 69-year-old lady who had NF I. Considering the rare association of carcinomas with NF I and finding that both the NF I gene and a breast cancer pre-disposition gene, BRCA 1 are located in close proximity on chromosome 17q makes the association of these two conditions intriguing.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=2;spage=166;epage=168;aulast=JinkalaAssociationcarcinoma breastneurofibromatosis I |
| spellingShingle | Sree Rekha Jinkala Nachiappa Ganesh Rajesh Arvind Ramkumar Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? Indian Journal of Pathology and Microbiology Association carcinoma breast neurofibromatosis I |
| title | Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? |
| title_full | Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? |
| title_fullStr | Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? |
| title_full_unstemmed | Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? |
| title_short | Basal like carcinoma of breast in patient with neurofibromatosis I: An association or co-existence? |
| title_sort | basal like carcinoma of breast in patient with neurofibromatosis i an association or co existence |
| topic | Association carcinoma breast neurofibromatosis I |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2013;volume=56;issue=2;spage=166;epage=168;aulast=Jinkala |
| work_keys_str_mv | AT sreerekhajinkala basallikecarcinomaofbreastinpatientwithneurofibromatosisianassociationorcoexistence AT nachiappaganeshrajesh basallikecarcinomaofbreastinpatientwithneurofibromatosisianassociationorcoexistence AT arvindramkumar basallikecarcinomaofbreastinpatientwithneurofibromatosisianassociationorcoexistence |