Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand

Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand

T-box riboswitches are cis-regulatory RNA elements that regulate the expression of proteins involved in amino acid biosynthesis and transport by binding to specific tRNAs and sensing their aminoacylation state. While the T-box modular structural elements that recognize different parts of a tRNA have...

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Bibliographic Details
Main Authors: Jiacheng Zhang, Bhaskar Chetnani, Eric D Cormack, Dulce Alonso, Wei Liu, Alfonso Mondragón, Jingyi Fei
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
riboswitch
T-box
smFRET
gene regulation
Online Access:https://elifesciences.org/articles/39518

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