Long-range GABAergic projections contribute to cortical feedback control of sensory processing
Classically, corticofugal feedback projections that adjust sensory processing are excitatory. Here, the authors uncover the presence of top-down inhibitory projections from cortical GABAergic neurons in the olfactory system, which directly inhibit olfactory bulb circuits.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34513-0 |
| _version_ | 1798019128156487680 |
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| author | Camille Mazo Antoine Nissant Soham Saha Enzo Peroni Pierre-Marie Lledo Gabriel Lepousez |
| author_facet | Camille Mazo Antoine Nissant Soham Saha Enzo Peroni Pierre-Marie Lledo Gabriel Lepousez |
| author_sort | Camille Mazo |
| collection | DOAJ |
| description | Classically, corticofugal feedback projections that adjust sensory processing are excitatory. Here, the authors uncover the presence of top-down inhibitory projections from cortical GABAergic neurons in the olfactory system, which directly inhibit olfactory bulb circuits. |
| first_indexed | 2024-04-11T16:35:41Z |
| format | Article |
| id | doaj.art-31eab6ae75b94e1bab1426e6b27a7185 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T16:35:41Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-31eab6ae75b94e1bab1426e6b27a71852022-12-22T04:13:51ZengNature PortfolioNature Communications2041-17232022-11-0113112010.1038/s41467-022-34513-0Long-range GABAergic projections contribute to cortical feedback control of sensory processingCamille Mazo0Antoine Nissant1Soham Saha2Enzo Peroni3Pierre-Marie Lledo4Gabriel Lepousez5Institut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitInstitut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitInstitut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitInstitut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitInstitut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitInstitut Pasteur, Université Paris Cité, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Perception and Memory UnitClassically, corticofugal feedback projections that adjust sensory processing are excitatory. Here, the authors uncover the presence of top-down inhibitory projections from cortical GABAergic neurons in the olfactory system, which directly inhibit olfactory bulb circuits.https://doi.org/10.1038/s41467-022-34513-0 |
| spellingShingle | Camille Mazo Antoine Nissant Soham Saha Enzo Peroni Pierre-Marie Lledo Gabriel Lepousez Long-range GABAergic projections contribute to cortical feedback control of sensory processing Nature Communications |
| title | Long-range GABAergic projections contribute to cortical feedback control of sensory processing |
| title_full | Long-range GABAergic projections contribute to cortical feedback control of sensory processing |
| title_fullStr | Long-range GABAergic projections contribute to cortical feedback control of sensory processing |
| title_full_unstemmed | Long-range GABAergic projections contribute to cortical feedback control of sensory processing |
| title_short | Long-range GABAergic projections contribute to cortical feedback control of sensory processing |
| title_sort | long range gabaergic projections contribute to cortical feedback control of sensory processing |
| url | https://doi.org/10.1038/s41467-022-34513-0 |
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