Diagnostic and therapeutic approach of diabetic ketoacidosis in children and adolescents in the emergency department = Enfoque diagnóstico y terapéutico de la cetoacidosis diabética en niños y adolescentes en el servicio de urgencias
Diabetic ketoacidosis (DKA) is the most frequent complication in children with type 1 diabetes. DKA is due to a partial or complete insulin deficit, associated with an increase of counterregulatory hormones, which leads to the biochemical alterations that define the disease: hyperglycemia, metabolic...
Main Authors: | , |
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Format: | Article |
Language: | Spanish |
Published: |
Universidad de Antioquia
2013-07-01
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Series: | Iatreia |
Subjects: | |
Online Access: | http://www.iatreia.udea.edu.co/index.php/iatreia/article/view/14285/13599 |
Summary: | Diabetic ketoacidosis (DKA) is the most frequent complication in children with type 1 diabetes. DKA is due to a partial or complete insulin deficit, associated with an increase of counterregulatory hormones, which leads to the biochemical alterations that define the disease: hyperglycemia, metabolic acidosis and ketonemia. Most DKA related deaths are caused by complications associated with the initial treatment. To prevent complications, an adequate assessment in the emergency service is essential; gradual reposition of fluids, dextrose supplementation during hydration, and insulin therapy are necessary. This paper is a critical review of the physiopathology, clinical manifestations, treatment and main complications of DKA. |
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ISSN: | 0121-0793 2011-7965 |