BioGPS descriptors for rational engineering of enzyme promiscuity and structure based bioinformatic analysis.

BioGPS descriptors for rational engineering of enzyme promiscuity and structure based bioinformatic analysis.

A new bioinformatic methodology was developed founded on the Unsupervised Pattern Cognition Analysis of GRID-based BioGPS descriptors (Global Positioning System in Biological Space). The procedure relies entirely on three-dimensional structure analysis of enzymes and does not stem from sequence or s...

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Bibliographic Details
Main Authors: Valerio Ferrario, Lydia Siragusa, Cynthia Ebert, Massimo Baroni, Marco Foscato, Gabriele Cruciani, Lucia Gardossi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4212942?pdf=render

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