Clinical and morphological features of large-cell neuroendocrine carcinomas and small-cell lung carcinomas expressing the DLL3 and ASCL1 oncoproteins

Clinical and morphological features of large-cell neuroendocrine carcinomas and small-cell lung carcinomas expressing the DLL3 and ASCL1 oncoproteins

Abstract Intratumoral similarities and differences between large-cell neuroendocrine carcinomas (LCNECs) and small-cell lung carcinomas (SCLCs) are determined partially by the Notch signaling pathway, which controls the switch from neuroendocrine to slight/non-neuroendocrine cell fate. LCNECs are di...

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Bibliographic Details
Main Authors: T.G. Prieto, C.M. Baldavira, J. Machado-Rugolo, E.H.R. Olivieri, E.C.A. da Silva, V.G. Silva, A.M. Ab'Saber, T.Y. Takagaki, V.L. Capelozzi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2023-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Large-cell neuroendocrine carcinomas
Small-cell lung carcinomas
Immunohistochemistry
Digital analysis
Transmission electron microscopy
DLL3/ASCL1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100697&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100697&tlng=en

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