Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes

Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes

Abstract Background Placental dysfunction, a root cause of common syndromes affecting human pregnancy, such as preeclampsia (PE), fetal growth restriction (FGR), and spontaneous preterm delivery (sPTD), remains poorly defined. These common, yet clinically disparate obstetrical syndromes share simila...

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Bibliographic Details
Main Authors: Oren Barak, Tyler Lovelace, Samantha Piekos, Tianjiao Chu, Zhishen Cao, Elena Sadovsky, Jean-Francois Mouillet, Yingshi Ouyang, W. Tony Parks, Leroy Hood, Nathan D. Price, Panayiotis V. Benos, Yoel Sadovsky
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Medicine
Subjects:
Pregnancy
Placenta
Multiomics
Similarity network fusion
Online Access:https://doi.org/10.1186/s12916-023-03054-8

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