Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus

Prostate adenocarcinoma is the most common malignancy in males in the United States and is typically highly treatable. Herein we present a case report of a male with a history of prostate adenocarcinoma previously managed with definitive radiation therapy who presented with sudden onset diplopia and...

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Main Authors: Jennifer E. Douglas, John Y.K. Lee, Karthik Rajasekaran
Format: Article
Language:English
Published: Karger Publishers 2020-10-01
Series:Biomedicine Hub
Subjects:
Online Access:https://www.karger.com/Article/FullText/510303
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author Jennifer E. Douglas
John Y.K. Lee
Karthik Rajasekaran
author_facet Jennifer E. Douglas
John Y.K. Lee
Karthik Rajasekaran
author_sort Jennifer E. Douglas
collection DOAJ
description Prostate adenocarcinoma is the most common malignancy in males in the United States and is typically highly treatable. Herein we present a case report of a male with a history of prostate adenocarcinoma previously managed with definitive radiation therapy who presented with sudden onset diplopia and examination consistent with an abducens palsy. He was ultimately found to have prostate adenocarcinoma metastatic to the clivus causing cranial neuropathy, and was referred for systemic chemotherapy and palliative Cyberknife stereotactic radiosurgery. While relatively rare, metastatic disease should be included in the differential diagnosis of atypical skull base lesions.
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spelling doaj.art-31f6feb74682457bb3d26669e517b3fc2022-12-21T23:58:22ZengKarger PublishersBiomedicine Hub2296-68702020-10-0153717410.1159/000510303510303Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the ClivusJennifer E. DouglasJohn Y.K. LeeKarthik RajasekaranProstate adenocarcinoma is the most common malignancy in males in the United States and is typically highly treatable. Herein we present a case report of a male with a history of prostate adenocarcinoma previously managed with definitive radiation therapy who presented with sudden onset diplopia and examination consistent with an abducens palsy. He was ultimately found to have prostate adenocarcinoma metastatic to the clivus causing cranial neuropathy, and was referred for systemic chemotherapy and palliative Cyberknife stereotactic radiosurgery. While relatively rare, metastatic disease should be included in the differential diagnosis of atypical skull base lesions.https://www.karger.com/Article/FullText/510303skull basesellar massclival metastasiscranial neuropathyprostate adenocarcinoma
spellingShingle Jennifer E. Douglas
John Y.K. Lee
Karthik Rajasekaran
Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
Biomedicine Hub
skull base
sellar mass
clival metastasis
cranial neuropathy
prostate adenocarcinoma
title Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
title_full Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
title_fullStr Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
title_full_unstemmed Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
title_short Cranial Nerve VI Palsy as Presenting Sign of Previously Undiagnosed Metastatic Prostate Adenocarcinoma to the Clivus
title_sort cranial nerve vi palsy as presenting sign of previously undiagnosed metastatic prostate adenocarcinoma to the clivus
topic skull base
sellar mass
clival metastasis
cranial neuropathy
prostate adenocarcinoma
url https://www.karger.com/Article/FullText/510303
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