5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability

5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability

Summary: Many psychiatric diseases have been associated with serotonin (5-HT) neuron dysfunction. The firing of 5-HT neurons is known to be under 5-HT1A receptor-mediated autoinhibition, but functional consequences of coexpressed receptors are unknown. Using co-immunoprecipitation, BRET, confocal, a...

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Bibliographic Details
Main Authors: Amina Benhadda, Célia Delhaye, Imane Moutkine, Xavier Marques, Marion Russeau, Corentin Le Magueresse, Anne Roumier, Sabine Lévi, Luc Maroteaux
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Neuroscience
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014785

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