Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis
Granulicatella adiacens, a nutritionally variant streptococci (NVS) is a well described organism associated with endocarditis. Previously communicated cases have documented the use of double beta-lactam therapy with ampicillin and ceftriaxone to treat patients with infective endocarditis due to Ente...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | IDCases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221425092100038X |
| _version_ | 1818891939839213568 |
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| author | S. Khan C. Urban V. Singh D. Liu S. Segal-Maurer Y. Parmar J. Yoon |
| author_facet | S. Khan C. Urban V. Singh D. Liu S. Segal-Maurer Y. Parmar J. Yoon |
| author_sort | S. Khan |
| collection | DOAJ |
| description | Granulicatella adiacens, a nutritionally variant streptococci (NVS) is a well described organism associated with endocarditis. Previously communicated cases have documented the use of double beta-lactam therapy with ampicillin and ceftriaxone to treat patients with infective endocarditis due to Enterococcus faecalis and Streptocossus pneumoniae. We describe the first case of Granulicatella adiacens infective endocarditis in a patient successfully treated with the combination of intravenous ampicillin and ceftriaxone and document their synergistic activity. |
| first_indexed | 2024-12-19T17:48:47Z |
| format | Article |
| id | doaj.art-31f9a41cfd5f41f2a54dee136412c5a1 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-19T17:48:47Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-31f9a41cfd5f41f2a54dee136412c5a12022-12-21T20:11:59ZengElsevierIDCases2214-25092021-01-0124e01082Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditisS. Khan0C. Urban1V. Singh2D. Liu3S. Segal-Maurer4Y. Parmar5J. Yoon6The Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USAThe Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USA; Weill Cornell Medical College, Cornell University, NY, 10065, USA; Corresponding author at: The Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USA.Department of Pathology, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USADepartment of Pathology, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USAThe Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USA; Weill Cornell Medical College, Cornell University, NY, 10065, USADepartment of Cardiology, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USAThe Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main Street, Flushing, NY, 11355, USAGranulicatella adiacens, a nutritionally variant streptococci (NVS) is a well described organism associated with endocarditis. Previously communicated cases have documented the use of double beta-lactam therapy with ampicillin and ceftriaxone to treat patients with infective endocarditis due to Enterococcus faecalis and Streptocossus pneumoniae. We describe the first case of Granulicatella adiacens infective endocarditis in a patient successfully treated with the combination of intravenous ampicillin and ceftriaxone and document their synergistic activity.http://www.sciencedirect.com/science/article/pii/S221425092100038XInfective endocarditisGranulicatella adiacensDouble beta-lactam therapySynergy |
| spellingShingle | S. Khan C. Urban V. Singh D. Liu S. Segal-Maurer Y. Parmar J. Yoon Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis IDCases Infective endocarditis Granulicatella adiacens Double beta-lactam therapy Synergy |
| title | Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis |
| title_full | Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis |
| title_fullStr | Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis |
| title_full_unstemmed | Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis |
| title_short | Novel double beta-lactam therapy for Granulicatella adiacens infective endocarditis |
| title_sort | novel double beta lactam therapy for granulicatella adiacens infective endocarditis |
| topic | Infective endocarditis Granulicatella adiacens Double beta-lactam therapy Synergy |
| url | http://www.sciencedirect.com/science/article/pii/S221425092100038X |
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