Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease

Abstract Inflammation is a pathological hallmark of Parkinson’s disease (PD). Chronic pro-inflammatory responses contribute to the loss of neurons in the neurodegenerative process. The present study was undertaken to define the peripheral innate and adaptive immune contributions to inflammation in p...

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Bibliographic Details
Main Authors: Aaron D. Thome, Farah Atassi, Jinghong Wang, Alireza Faridar, Weihua Zhao, Jason R. Thonhoff, David R. Beers, Eugene C. Lai, Stanley H. Appel
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00188-5

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