MicroRNA-7 Inhibits Rotavirus Replication by Targeting Viral NSP5 In Vivo and In Vitro

MicroRNA-7 Inhibits Rotavirus Replication by Targeting Viral NSP5 In Vivo and In Vitro

Rotavirus (RV) is the major causes of severe diarrhea in infants and young children under five years of age. There are no effective drugs for the treatment of rotavirus in addition to preventive live attenuated vaccine. Recent evidence demonstrates that microRNAs (miRNAs) can affect RNA virus replic...

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Bibliographic Details
Main Authors: Yan Zhou, Linlin Chen, Jing Du, Xiaoqing Hu, Yuping Xie, Jinyuan Wu, Xiaochen Lin, Na Yin, Maosheng Sun, Hongjun Li
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Viruses
Subjects:
rotavirus
microrna 7
non-structural protein 5
gene replication
anti-viral
Online Access:https://www.mdpi.com/1999-4915/12/2/209

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