MicroRNAs and Hypertension

MicroRNAs (miRNAs) are non-coding, highly conserved RNAs found in all biological fluids, that are emerging as master regulators of gene expression, consequently impacting a variety of biological processes in both healthy and diseased environments. There are still certain limitations regarding analys...

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Main Authors: Nikolina Kolobarić, Ines Drenjančević
Format: Article
Language:English
Published: Faculty of Medicine Osijek 2022-04-01
Series:Southeastern European Medical Journal
Subjects:
Online Access:http://seemedj.mefos.unios.hr/index.php/seemedj/article/view/244/124
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author Nikolina Kolobarić
Ines Drenjančević
author_facet Nikolina Kolobarić
Ines Drenjančević
author_sort Nikolina Kolobarić
collection DOAJ
description MicroRNAs (miRNAs) are non-coding, highly conserved RNAs found in all biological fluids, that are emerging as master regulators of gene expression, consequently impacting a variety of biological processes in both healthy and diseased environments. There are still certain limitations regarding analysis of circulating miRNAs, specifically concerning standardisation and accuracy of obtained data. However, there is an indisputable therapeutic and diagnostic potential, confirmed by recent research. Hypertension, as one of the leading causes of death in modern world, has been in the focus of scientific society for several decades now. So, it is of outmost importance to investigate and pinpoint appropriate miRNAs for early indication and diagnosis of hypertension in general population. More in vivo and clinical research is necessary in animal and human models in order to exploit the full potential of this novel technology.
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spelling doaj.art-32056e1114b7489b9cf1f6a5cb57c90c2022-12-22T02:00:56ZengFaculty of Medicine OsijekSoutheastern European Medical Journal2459-94842022-04-0161536710.26332/seemedj.v6i1.244MicroRNAs and HypertensionNikolina Kolobarić0https://orcid.org/0000-0002-5649-8317Ines Drenjančević1https://orcid.org/0000-0003-4964-7721Department of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, CroatiaDepartment of Physiology and Immunology, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Croatia; Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek, CroatiaMicroRNAs (miRNAs) are non-coding, highly conserved RNAs found in all biological fluids, that are emerging as master regulators of gene expression, consequently impacting a variety of biological processes in both healthy and diseased environments. There are still certain limitations regarding analysis of circulating miRNAs, specifically concerning standardisation and accuracy of obtained data. However, there is an indisputable therapeutic and diagnostic potential, confirmed by recent research. Hypertension, as one of the leading causes of death in modern world, has been in the focus of scientific society for several decades now. So, it is of outmost importance to investigate and pinpoint appropriate miRNAs for early indication and diagnosis of hypertension in general population. More in vivo and clinical research is necessary in animal and human models in order to exploit the full potential of this novel technology.http://seemedj.mefos.unios.hr/index.php/seemedj/article/view/244/124blood pressurehypertensionmicrornassodium chloride
spellingShingle Nikolina Kolobarić
Ines Drenjančević
MicroRNAs and Hypertension
Southeastern European Medical Journal
blood pressure
hypertension
micrornas
sodium chloride
title MicroRNAs and Hypertension
title_full MicroRNAs and Hypertension
title_fullStr MicroRNAs and Hypertension
title_full_unstemmed MicroRNAs and Hypertension
title_short MicroRNAs and Hypertension
title_sort micrornas and hypertension
topic blood pressure
hypertension
micrornas
sodium chloride
url http://seemedj.mefos.unios.hr/index.php/seemedj/article/view/244/124
work_keys_str_mv AT nikolinakolobaric micrornasandhypertension
AT inesdrenjancevic micrornasandhypertension