Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics

Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics

Abstract Single‐cell technologies allow measuring chromatin accessibility and gene expression in each cell, but jointly utilizing both layers to map bona fide gene regulatory networks and enhancers remains challenging. Here, we generate independent single‐cell RNA‐seq and single‐cell ATAC‐seq atlase...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Carmen Bravo González‐Blas, Xiao‐Jiang Quan, Ramon Duran‐Romaña, Ibrahim Ihsan Taskiran, Duygu Koldere, Kristofer Davie, Valerie Christiaens, Samira Makhzami, Gert Hulselmans, Maxime de Waegeneer, David Mauduit, Suresh Poovathingal, Sara Aibar, Stein Aerts
Format: Artykuł
Język:English
Wydane: Springer Nature 2020-05-01
Seria:Molecular Systems Biology
Hasła przedmiotowe:
enhancer detection
eye‐antennal disc
gene regulation
single‐cell omics
spatial integration
Dostęp online:https://doi.org/10.15252/msb.20209438

Internet

https://doi.org/10.15252/msb.20209438

Podobne zapisy