The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients
Background: Transplanted patients are frail individuals who may be affected by diastolic dysfunction, leading to a decrease in exercise tolerance. Previous studies have reported that certain ECG and echocardiographic parameters (such as the P-wave interval, PQ interval, P-wave dispersion, Tend-P int...
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MDPI AG
2023-08-01
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| Online Access: | https://www.mdpi.com/2413-4155/5/3/34 |
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| author | Laura Stefani Goffredo Orlandi Marco Corsi Edoardo Falconi Roberto Palazzo Alessio Pellegrino Pietro Amedeo Modesti |
| author_facet | Laura Stefani Goffredo Orlandi Marco Corsi Edoardo Falconi Roberto Palazzo Alessio Pellegrino Pietro Amedeo Modesti |
| author_sort | Laura Stefani |
| collection | DOAJ |
| description | Background: Transplanted patients are frail individuals who may be affected by diastolic dysfunction, leading to a decrease in exercise tolerance. Previous studies have reported that certain ECG and echocardiographic parameters (such as the P-wave interval, PQ interval, P-wave dispersion, Tend-P interval, QTc interval, and strain) can support the diagnosis of diastolic dysfunction when the ejection fraction is preserved. This study aimed to examine the potential diagnostic contribution of specific ECG and deformation parameters in transplanted recipients, who are at a high risk of heart failure. Materials and Methods: A group of 33 transplanted subjects (17 renal and 16 liver) were categorized using two scores for heart failure with preserved ejection fraction (HFpEF). Additionally, they underwent evaluation based on ECG parameters (P-wave interval, PQ interval, Pwave dispersion, and Tend-P QTc) and echocardiographic deformation parameters (strain and twist). The Student’s t-test was used for statistical analysis. Results: The two scores identified different numbers of excludable and not excludable subjects potentially affected by HFpEF. The not excludable group presented ECG parameters with significantly higher values (P-wave, PQ interval, posterior wall diastole, and Tend-P, all with <i>p</i> ≤ 0.05) and significantly lower 4D strain and twist values (<i>p</i> < 0.05) Conclusions: There is evidence for a significant diagnostic contribution of additional ECG and echo strain parameters in an early phase of diastolic dysfunction in subjects potentially affected by HFpEF. |
| first_indexed | 2024-03-10T22:03:08Z |
| format | Article |
| id | doaj.art-3208024c54414444b99b46c3e13b251c |
| institution | Directory Open Access Journal |
| issn | 2413-4155 |
| language | English |
| last_indexed | 2024-03-10T22:03:08Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sci |
| spelling | doaj.art-3208024c54414444b99b46c3e13b251c2023-11-19T12:52:00ZengMDPI AGSci2413-41552023-08-01533410.3390/sci5030034The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted PatientsLaura Stefani0Goffredo Orlandi1Marco Corsi2Edoardo Falconi3Roberto Palazzo4Alessio Pellegrino5Pietro Amedeo Modesti6Clinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyClinical and Experimental Department, Sports Medicine Center, University of Florence, 50134 Firenze, ItalyBackground: Transplanted patients are frail individuals who may be affected by diastolic dysfunction, leading to a decrease in exercise tolerance. Previous studies have reported that certain ECG and echocardiographic parameters (such as the P-wave interval, PQ interval, P-wave dispersion, Tend-P interval, QTc interval, and strain) can support the diagnosis of diastolic dysfunction when the ejection fraction is preserved. This study aimed to examine the potential diagnostic contribution of specific ECG and deformation parameters in transplanted recipients, who are at a high risk of heart failure. Materials and Methods: A group of 33 transplanted subjects (17 renal and 16 liver) were categorized using two scores for heart failure with preserved ejection fraction (HFpEF). Additionally, they underwent evaluation based on ECG parameters (P-wave interval, PQ interval, Pwave dispersion, and Tend-P QTc) and echocardiographic deformation parameters (strain and twist). The Student’s t-test was used for statistical analysis. Results: The two scores identified different numbers of excludable and not excludable subjects potentially affected by HFpEF. The not excludable group presented ECG parameters with significantly higher values (P-wave, PQ interval, posterior wall diastole, and Tend-P, all with <i>p</i> ≤ 0.05) and significantly lower 4D strain and twist values (<i>p</i> < 0.05) Conclusions: There is evidence for a significant diagnostic contribution of additional ECG and echo strain parameters in an early phase of diastolic dysfunction in subjects potentially affected by HFpEF.https://www.mdpi.com/2413-4155/5/3/34HFpEForgan transplantationH2FPEFHFA-PEFexercise prescription |
| spellingShingle | Laura Stefani Goffredo Orlandi Marco Corsi Edoardo Falconi Roberto Palazzo Alessio Pellegrino Pietro Amedeo Modesti The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients Sci HFpEF organ transplantation H2FPEF HFA-PEF exercise prescription |
| title | The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients |
| title_full | The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients |
| title_fullStr | The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients |
| title_full_unstemmed | The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients |
| title_short | The Additional Diagnostic Value of Electrocardiogram and Strain Patterns in Transplanted Patients |
| title_sort | additional diagnostic value of electrocardiogram and strain patterns in transplanted patients |
| topic | HFpEF organ transplantation H2FPEF HFA-PEF exercise prescription |
| url | https://www.mdpi.com/2413-4155/5/3/34 |
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