The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae.
Flos Lonicerae Japonicae (FLJ) is an important cash crop in eastern Asia, and it is an anti-inflammatory Traditional Chinese Medicine. There are large variations in the quality of the marketed FLJ products. To find marker ingredients useful for quality control, a tandem technology integrating ultra-...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4014484?pdf=render |
| _version_ | 1830357980000813056 |
|---|---|
| author | Min Jiang Yan-qi Han Meng-ge Zhou Hong-zhi Zhao Xue Xiao Yuan-yuan Hou Jie Gao Gang Bai Guo-an Luo |
| author_facet | Min Jiang Yan-qi Han Meng-ge Zhou Hong-zhi Zhao Xue Xiao Yuan-yuan Hou Jie Gao Gang Bai Guo-an Luo |
| author_sort | Min Jiang |
| collection | DOAJ |
| description | Flos Lonicerae Japonicae (FLJ) is an important cash crop in eastern Asia, and it is an anti-inflammatory Traditional Chinese Medicine. There are large variations in the quality of the marketed FLJ products. To find marker ingredients useful for quality control, a tandem technology integrating ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF), principal component analysis (PCA), heat map analysis and hierarchical cluster analysis coupled with a NF-κB luciferase reporter gene assay were used to identify the different ingredients from the green bud, white bud, flowering stage and leaf stages, as well as to screen the anti-inflammatory activity of FLJ compositions. As flowering progressed, the anti-inflammatory effects of FLJ gradually decreased; however, chlorogenic acid, swertiamarin and sweroside should be used to evaluate the quality of FLJ products. |
| first_indexed | 2024-12-20T02:33:05Z |
| format | Article |
| id | doaj.art-320b91c5a2af4a0ab6becda48e6bac2b |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T02:33:05Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-320b91c5a2af4a0ab6becda48e6bac2b2022-12-21T19:56:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0195e9621410.1371/journal.pone.0096214The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae.Min JiangYan-qi HanMeng-ge ZhouHong-zhi ZhaoXue XiaoYuan-yuan HouJie GaoGang BaiGuo-an LuoFlos Lonicerae Japonicae (FLJ) is an important cash crop in eastern Asia, and it is an anti-inflammatory Traditional Chinese Medicine. There are large variations in the quality of the marketed FLJ products. To find marker ingredients useful for quality control, a tandem technology integrating ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF), principal component analysis (PCA), heat map analysis and hierarchical cluster analysis coupled with a NF-κB luciferase reporter gene assay were used to identify the different ingredients from the green bud, white bud, flowering stage and leaf stages, as well as to screen the anti-inflammatory activity of FLJ compositions. As flowering progressed, the anti-inflammatory effects of FLJ gradually decreased; however, chlorogenic acid, swertiamarin and sweroside should be used to evaluate the quality of FLJ products.http://europepmc.org/articles/PMC4014484?pdf=render |
| spellingShingle | Min Jiang Yan-qi Han Meng-ge Zhou Hong-zhi Zhao Xue Xiao Yuan-yuan Hou Jie Gao Gang Bai Guo-an Luo The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. PLoS ONE |
| title | The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. |
| title_full | The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. |
| title_fullStr | The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. |
| title_full_unstemmed | The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. |
| title_short | The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae. |
| title_sort | screening research of anti inflammatory bioactive markers from different flowering phases of flos lonicerae japonicae |
| url | http://europepmc.org/articles/PMC4014484?pdf=render |
| work_keys_str_mv | AT minjiang thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT yanqihan thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT menggezhou thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT hongzhizhao thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT xuexiao thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT yuanyuanhou thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT jiegao thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT gangbai thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT guoanluo thescreeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT minjiang screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT yanqihan screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT menggezhou screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT hongzhizhao screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT xuexiao screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT yuanyuanhou screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT jiegao screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT gangbai screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae AT guoanluo screeningresearchofantiinflammatorybioactivemarkersfromdifferentfloweringphasesofflosloniceraejaponicae |