Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan
Background: Congenital malformations are the leading factor of perinatal death and childhood morbidity. Present study was aimed to compare congenital malformations detected prenatally by ultrasonography and postnatally by fetal autopsy and also the quantum of additional information autopsy can provi...
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| Format: | Article |
| Language: | English |
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BKL Walawalkar Rural Medical College & Hospital
2022-09-01
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| Series: | Walawalkar International Medical Journal |
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| Online Access: | http://www.wimjournal.com |
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| author | Maulika Agarwal Kunda Jagadale Manjiri Karandikar Ravindra Nimbargi Narayanan Mani Vijeeta Ranadive |
| author_facet | Maulika Agarwal Kunda Jagadale Manjiri Karandikar Ravindra Nimbargi Narayanan Mani Vijeeta Ranadive |
| author_sort | Maulika Agarwal |
| collection | DOAJ |
| description | Background: Congenital malformations are the leading factor of perinatal death and childhood morbidity. Present study was aimed to compare congenital malformations detected prenatally by ultrasonography and postnatally by fetal autopsy and also the quantum of additional information autopsy can provide. Material and Methods: Present study was hospital based cross sectional studyof fetal and neonatal autopsies conducted in cases terminated for anomalies, intrauterine fetal demise and stillbirths in the second and third trimester. First trimester cases were excluded. Results: Eighty one fetal / neonatal autopsies were studied. Majority were terminated pregnancies before 24 weeks of gestation for congenital anomalies (93 %) and birth weight less than 1000 grams (75.3 %). Ultrasonography(USG) showed concordance with autopsy in 78% cases, discordance in 5% cases and additional findings were seen in 6% cases. Common congenital anomalies were central nervous system (CNS) defects (41.4 %), genitourinary(GU) defects (21.9 %), congenital heart defects (CHD) (4.9%), gastrointestinal(GI) defects (9.75%), musculoskeletal defects (14.6%), respiratory defects (7.3 %), cystic hygroma (1.23%) and fetal hydrops (1.23%). Autopsy added diagnosis in 05 cases (6 %) as bilobed right lung (2), omphalocele (1), anencephaly (1) and horseshoe shaped kidney (1).Conclusion: Parents should be encouraged for autopsy in view of counseling for future pregnancies. Anomaly scan predicts the malformations in the fetus but autopsy is necessary to confirm the anomaly and also to look for additional malformations. Thus autopsy can help parents in planning and management of future pregnancies. |
| first_indexed | 2024-04-12T00:57:38Z |
| format | Article |
| id | doaj.art-320d58ad4b484ba0ac70a3d029dfef78 |
| institution | Directory Open Access Journal |
| issn | 2395-0684 |
| language | English |
| last_indexed | 2024-04-12T00:57:38Z |
| publishDate | 2022-09-01 |
| publisher | BKL Walawalkar Rural Medical College & Hospital |
| record_format | Article |
| series | Walawalkar International Medical Journal |
| spelling | doaj.art-320d58ad4b484ba0ac70a3d029dfef782022-12-22T03:54:35ZengBKL Walawalkar Rural Medical College & HospitalWalawalkar International Medical Journal2395-06842022-09-0192813Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly ScanMaulika Agarwal0Kunda Jagadale1 Manjiri Karandikar2 Ravindra Nimbargi3Narayanan Mani4Vijeeta Ranadive5Department of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaDepartment of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaDepartment of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaDepartment of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaDepartment of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaDepartment of Pathology, Bharati Vidyapeeth Deemed to be University Medical College and Hospital, Pune- 411043, Maharashtra, IndiaBackground: Congenital malformations are the leading factor of perinatal death and childhood morbidity. Present study was aimed to compare congenital malformations detected prenatally by ultrasonography and postnatally by fetal autopsy and also the quantum of additional information autopsy can provide. Material and Methods: Present study was hospital based cross sectional studyof fetal and neonatal autopsies conducted in cases terminated for anomalies, intrauterine fetal demise and stillbirths in the second and third trimester. First trimester cases were excluded. Results: Eighty one fetal / neonatal autopsies were studied. Majority were terminated pregnancies before 24 weeks of gestation for congenital anomalies (93 %) and birth weight less than 1000 grams (75.3 %). Ultrasonography(USG) showed concordance with autopsy in 78% cases, discordance in 5% cases and additional findings were seen in 6% cases. Common congenital anomalies were central nervous system (CNS) defects (41.4 %), genitourinary(GU) defects (21.9 %), congenital heart defects (CHD) (4.9%), gastrointestinal(GI) defects (9.75%), musculoskeletal defects (14.6%), respiratory defects (7.3 %), cystic hygroma (1.23%) and fetal hydrops (1.23%). Autopsy added diagnosis in 05 cases (6 %) as bilobed right lung (2), omphalocele (1), anencephaly (1) and horseshoe shaped kidney (1).Conclusion: Parents should be encouraged for autopsy in view of counseling for future pregnancies. Anomaly scan predicts the malformations in the fetus but autopsy is necessary to confirm the anomaly and also to look for additional malformations. Thus autopsy can help parents in planning and management of future pregnancies.http://www.wimjournal.comfetal autopsyperinatal autopsycongenitalanomaliesstillbirths. |
| spellingShingle | Maulika Agarwal Kunda Jagadale Manjiri Karandikar Ravindra Nimbargi Narayanan Mani Vijeeta Ranadive Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan Walawalkar International Medical Journal fetal autopsy perinatal autopsy congenital anomalies stillbirths. |
| title | Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan |
| title_full | Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan |
| title_fullStr | Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan |
| title_full_unstemmed | Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan |
| title_short | Fetal and Neonatal Autopsy: A Morphological Study and Correlation with Prenatal Anomaly Scan |
| title_sort | fetal and neonatal autopsy a morphological study and correlation with prenatal anomaly scan |
| topic | fetal autopsy perinatal autopsy congenital anomalies stillbirths. |
| url | http://www.wimjournal.com |
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