Impact of Mitophagy and Mitochondrial Unfolded Protein Response as New Adaptive Mechanisms Underlying Old Pathologies: Sarcopenia and Non-Alcoholic Fatty Liver Disease

Impact of Mitophagy and Mitochondrial Unfolded Protein Response as New Adaptive Mechanisms Underlying Old Pathologies: Sarcopenia and Non-Alcoholic Fatty Liver Disease

Mitochondria are the first-line defense of the cell in the presence of stressing processes that can induce mitochondrial dysfunction. Under these conditions, the activation of two axes is accomplished, namely, (i) the mitochondrial unfolded protein response (UPR<sup>mt</sup>) to promote...

Full description

Bibliographic Details
Main Authors: Rodrigo Urbina-Varela, Nataly Castillo, Luis A. Videla, Andrea del Campo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondrial homeostasis
aging
liver disease
skeletal muscle
Online Access:https://www.mdpi.com/1422-0067/21/20/7704

Similar Items

Similar Items