Research Progress in Focal Treatment of Prostate Cancer
Prostate cancer is the second most common malignant tumor in men worldwide, and its incidence is increasing in China. Treatment methods of prostate cancer include surgery, radiotherapy, chemotherapy, endocrine therapy, and local therapy. Compared to all treatment options for prostate cancer, local t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Asian Medical Press Ltd.(H.K.)
2023-06-01
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| Series: | Annals of Urologic Oncology |
| Subjects: | |
| Online Access: | http://auo.asmepress.com/articles/new-1-458.html |
| _version_ | 1797791723420647424 |
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| author | Songtao Cheng Shize Wang Jing Liu Jianlin Huang iannan Liu |
| author_facet | Songtao Cheng Shize Wang Jing Liu Jianlin Huang iannan Liu |
| author_sort | Songtao Cheng |
| collection | DOAJ |
| description | Prostate cancer is the second most common malignant tumor in men worldwide, and its incidence is increasing in China. Treatment methods of prostate cancer include surgery, radiotherapy, chemotherapy, endocrine therapy, and local therapy. Compared to all treatment options for prostate cancer, local treatment has the advantage of less trauma and fewer complications. With the wide application of PSA screening, improvement and enhancement of transperineal puncture technology under template positioning and the development of multi-parameter MRI, more and more low-grade and localized prostate cancer are detected. Most prostate cancer patients receive total gland therapy after diagnosis, but patients with localized prostate cancer may not benefit from treatment because of the side effects of total gland therapy. With the development of imaging technology and the "main focus" theory, focal therapy techniques have been greatly developed. Focal therapy (FT) is a treatment method for localized prostate cancer (Pca), which mainly targets low and medium-risk localized disease to reduce whole-gland treatment. Such as radical prostatectomy (RP) or the adverse effects of radical external radiotherapy, FT has the advantage of preserving more sexual and bladder function while controlling the tumor. The current focal therapy techniques used in clinic mainly include high-intensity focused ultrasound, focal laser ablation, cryotherapy, irreversible electroporation, and photodynamic therapy. In this study, we reviewed the clinical trials of focal therapy in recent years and found that high-intensity focused ultrasound and focal laser ablation have better failure-free survival and postoperative functional control. |
| first_indexed | 2024-03-13T02:23:50Z |
| format | Article |
| id | doaj.art-32121c58c738465fad9d70d733add5bf |
| institution | Directory Open Access Journal |
| issn | 2617-7765 2617-7773 |
| language | English |
| last_indexed | 2024-03-13T02:23:50Z |
| publishDate | 2023-06-01 |
| publisher | Asian Medical Press Ltd.(H.K.) |
| record_format | Article |
| series | Annals of Urologic Oncology |
| spelling | doaj.art-32121c58c738465fad9d70d733add5bf2023-06-30T06:51:23ZengAsian Medical Press Ltd.(H.K.)Annals of Urologic Oncology2617-77652617-77732023-06-0162798610.32948/auo.2023.06.24Research Progress in Focal Treatment of Prostate CancerSongtao Cheng0Shize Wang1Jing Liu2Jianlin Huang3iannan Liu4Department of Urology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.Department of Urology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.Department of Urology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.Department of Urology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.Department of Urology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China.Prostate cancer is the second most common malignant tumor in men worldwide, and its incidence is increasing in China. Treatment methods of prostate cancer include surgery, radiotherapy, chemotherapy, endocrine therapy, and local therapy. Compared to all treatment options for prostate cancer, local treatment has the advantage of less trauma and fewer complications. With the wide application of PSA screening, improvement and enhancement of transperineal puncture technology under template positioning and the development of multi-parameter MRI, more and more low-grade and localized prostate cancer are detected. Most prostate cancer patients receive total gland therapy after diagnosis, but patients with localized prostate cancer may not benefit from treatment because of the side effects of total gland therapy. With the development of imaging technology and the "main focus" theory, focal therapy techniques have been greatly developed. Focal therapy (FT) is a treatment method for localized prostate cancer (Pca), which mainly targets low and medium-risk localized disease to reduce whole-gland treatment. Such as radical prostatectomy (RP) or the adverse effects of radical external radiotherapy, FT has the advantage of preserving more sexual and bladder function while controlling the tumor. The current focal therapy techniques used in clinic mainly include high-intensity focused ultrasound, focal laser ablation, cryotherapy, irreversible electroporation, and photodynamic therapy. In this study, we reviewed the clinical trials of focal therapy in recent years and found that high-intensity focused ultrasound and focal laser ablation have better failure-free survival and postoperative functional control.http://auo.asmepress.com/articles/new-1-458.htmlprostate cancerfocal treatmenthigh intensity focused ultrasoundfocal laser ablationcryotherapy |
| spellingShingle | Songtao Cheng Shize Wang Jing Liu Jianlin Huang iannan Liu Research Progress in Focal Treatment of Prostate Cancer Annals of Urologic Oncology prostate cancer focal treatment high intensity focused ultrasound focal laser ablation cryotherapy |
| title | Research Progress in Focal Treatment of Prostate Cancer |
| title_full | Research Progress in Focal Treatment of Prostate Cancer |
| title_fullStr | Research Progress in Focal Treatment of Prostate Cancer |
| title_full_unstemmed | Research Progress in Focal Treatment of Prostate Cancer |
| title_short | Research Progress in Focal Treatment of Prostate Cancer |
| title_sort | research progress in focal treatment of prostate cancer |
| topic | prostate cancer focal treatment high intensity focused ultrasound focal laser ablation cryotherapy |
| url | http://auo.asmepress.com/articles/new-1-458.html |
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