Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions.
BACKGROUND: The risk of endobronchial ultrasound-guided transbronchial biopsy-related pneumothorax is a major concern and warrants further studies. The aim of our study was to estimate the risk of pneumothorax after this procedure and identify its risk factors. METHODS: From 2007 to 2011, 399 patien...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3492297?pdf=render |
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| author | Chun-Ta Huang Sheng-Yuan Ruan Wei-Yu Liao Yao-Wen Kuo Chi-Ying Lin Yi-Ju Tsai Chao-Chi Ho Chong-Jen Yu |
| author_facet | Chun-Ta Huang Sheng-Yuan Ruan Wei-Yu Liao Yao-Wen Kuo Chi-Ying Lin Yi-Ju Tsai Chao-Chi Ho Chong-Jen Yu |
| author_sort | Chun-Ta Huang |
| collection | DOAJ |
| description | BACKGROUND: The risk of endobronchial ultrasound-guided transbronchial biopsy-related pneumothorax is a major concern and warrants further studies. The aim of our study was to estimate the risk of pneumothorax after this procedure and identify its risk factors. METHODS: From 2007 to 2011, 399 patients who underwent endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions were included in this study. The variables analyzed included patient factors, lesion factors and procedure factors. Multivariate logistic regression analysis was used to identify independent risk factors for pneumothorax. RESULTS: The incidence of pneumothorax was 3.3% (13/399). Chest tube placement was required for 31% (4/13) of pneumothoraces. Independent risk factors for pneumothorax included pulmonary emphysema (OR, 55.09; 95% CI, 9.37-324.03; p<0.001) and probe position adjacent to the lesion (OR, 17.01; 95% CI, 2.85-101.64; p = 0.002). The number of biopsy specimens, age, sex, history of prior lung surgery and lesion size, location and character did not influence the risk of pneumothorax in our analyses. CONCLUSIONS: The risk of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy is low. To further reduce the risk of pneumothorax, every effort should be made to advance the endobronchial ultrasound probe into the bronchus where it is imaged within the target lesion before embarking on transbronchial biopsy. |
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| id | doaj.art-321836d115e84d92a0cdc1883a0e81d5 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T04:28:42Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj.art-321836d115e84d92a0cdc1883a0e81d52022-12-22T03:47:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-01711e4912510.1371/journal.pone.0049125Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions.Chun-Ta HuangSheng-Yuan RuanWei-Yu LiaoYao-Wen KuoChi-Ying LinYi-Ju TsaiChao-Chi HoChong-Jen YuBACKGROUND: The risk of endobronchial ultrasound-guided transbronchial biopsy-related pneumothorax is a major concern and warrants further studies. The aim of our study was to estimate the risk of pneumothorax after this procedure and identify its risk factors. METHODS: From 2007 to 2011, 399 patients who underwent endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions were included in this study. The variables analyzed included patient factors, lesion factors and procedure factors. Multivariate logistic regression analysis was used to identify independent risk factors for pneumothorax. RESULTS: The incidence of pneumothorax was 3.3% (13/399). Chest tube placement was required for 31% (4/13) of pneumothoraces. Independent risk factors for pneumothorax included pulmonary emphysema (OR, 55.09; 95% CI, 9.37-324.03; p<0.001) and probe position adjacent to the lesion (OR, 17.01; 95% CI, 2.85-101.64; p = 0.002). The number of biopsy specimens, age, sex, history of prior lung surgery and lesion size, location and character did not influence the risk of pneumothorax in our analyses. CONCLUSIONS: The risk of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy is low. To further reduce the risk of pneumothorax, every effort should be made to advance the endobronchial ultrasound probe into the bronchus where it is imaged within the target lesion before embarking on transbronchial biopsy.http://europepmc.org/articles/PMC3492297?pdf=render |
| spellingShingle | Chun-Ta Huang Sheng-Yuan Ruan Wei-Yu Liao Yao-Wen Kuo Chi-Ying Lin Yi-Ju Tsai Chao-Chi Ho Chong-Jen Yu Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. PLoS ONE |
| title | Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. |
| title_full | Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. |
| title_fullStr | Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. |
| title_full_unstemmed | Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. |
| title_short | Risk factors of pneumothorax after endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions. |
| title_sort | risk factors of pneumothorax after endobronchial ultrasound guided transbronchial biopsy for peripheral lung lesions |
| url | http://europepmc.org/articles/PMC3492297?pdf=render |
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