Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells.
HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). We describe here a novel post-transcriptional block in HIV-1 gene expression in resting CD4+ T cells from patients on HAART. This block involves the aber...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-07-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1487174?pdf=render |