A case of true allergy to amide local anesthetics in a parturient

IgE-mediated hypersensitivity reactions to amide local anesthetics (LAs) are very rare events in anesthesia practice. When such a reaction occurs, anesthesiologists are often left with numerous confounding causes of adverse e after LA administration. Most times, such reactions result from systemic t...

Full description

Bibliographic Details
Main Authors: Vijayanthi Vijayan, Adethen Gunasekaran, Sakthirajan Paneerselvam, Kirthiha Govindaraj
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Obstetric Anaesthesia and Critical Care
Subjects:
Online Access:http://www.joacc.com/article.asp?issn=2249-4472;year=2024;volume=14;issue=1;spage=73;epage=75;aulast=Vijayan
_version_ 1797246159989768192
author Vijayanthi Vijayan
Adethen Gunasekaran
Sakthirajan Paneerselvam
Kirthiha Govindaraj
author_facet Vijayanthi Vijayan
Adethen Gunasekaran
Sakthirajan Paneerselvam
Kirthiha Govindaraj
author_sort Vijayanthi Vijayan
collection DOAJ
description IgE-mediated hypersensitivity reactions to amide local anesthetics (LAs) are very rare events in anesthesia practice. When such a reaction occurs, anesthesiologists are often left with numerous confounding causes of adverse e after LA administration. Most times, such reactions result from systemic toxicity or non-hypersensitivity reactions. In the event of a true allergy to LA molecules, subsequent administration of the same drug can lead to life-threatening complications. Herewith, we report the successful diagnosis of LA allergy in a parturient who had a history of anaphylaxis following the administration of subarachnoid block with an unknown drug elsewhere. She presented to our institute for her second cesarean section. Skin prick testing was done after a dermatology consultation, which revealed a positive response to lignocaine, bupivacaine, and ropivacaine (preservative-free). She was taken up for elective cesarean section under general anesthesia with complete avoidance of LAs. Postoperative analgesia was instituted with intravenous patient-controlled fentanyl administration. The procedure and recovery were uneventful and both mother and baby were discharged without any issues.
first_indexed 2024-04-24T19:38:23Z
format Article
id doaj.art-321c86e80d19420c99c1468b7fd843f9
institution Directory Open Access Journal
issn 2249-4472
language English
last_indexed 2024-04-24T19:38:23Z
publishDate 2024-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Obstetric Anaesthesia and Critical Care
spelling doaj.art-321c86e80d19420c99c1468b7fd843f92024-03-25T11:28:14ZengWolters Kluwer Medknow PublicationsJournal of Obstetric Anaesthesia and Critical Care2249-44722024-01-01141737510.4103/JOACC.JOACC_10_23A case of true allergy to amide local anesthetics in a parturientVijayanthi VijayanAdethen GunasekaranSakthirajan PaneerselvamKirthiha GovindarajIgE-mediated hypersensitivity reactions to amide local anesthetics (LAs) are very rare events in anesthesia practice. When such a reaction occurs, anesthesiologists are often left with numerous confounding causes of adverse e after LA administration. Most times, such reactions result from systemic toxicity or non-hypersensitivity reactions. In the event of a true allergy to LA molecules, subsequent administration of the same drug can lead to life-threatening complications. Herewith, we report the successful diagnosis of LA allergy in a parturient who had a history of anaphylaxis following the administration of subarachnoid block with an unknown drug elsewhere. She presented to our institute for her second cesarean section. Skin prick testing was done after a dermatology consultation, which revealed a positive response to lignocaine, bupivacaine, and ropivacaine (preservative-free). She was taken up for elective cesarean section under general anesthesia with complete avoidance of LAs. Postoperative analgesia was instituted with intravenous patient-controlled fentanyl administration. The procedure and recovery were uneventful and both mother and baby were discharged without any issues.http://www.joacc.com/article.asp?issn=2249-4472;year=2024;volume=14;issue=1;spage=73;epage=75;aulast=Vijayanallergy testinganaphylaxislocal anestheticpregnancy
spellingShingle Vijayanthi Vijayan
Adethen Gunasekaran
Sakthirajan Paneerselvam
Kirthiha Govindaraj
A case of true allergy to amide local anesthetics in a parturient
Journal of Obstetric Anaesthesia and Critical Care
allergy testing
anaphylaxis
local anesthetic
pregnancy
title A case of true allergy to amide local anesthetics in a parturient
title_full A case of true allergy to amide local anesthetics in a parturient
title_fullStr A case of true allergy to amide local anesthetics in a parturient
title_full_unstemmed A case of true allergy to amide local anesthetics in a parturient
title_short A case of true allergy to amide local anesthetics in a parturient
title_sort case of true allergy to amide local anesthetics in a parturient
topic allergy testing
anaphylaxis
local anesthetic
pregnancy
url http://www.joacc.com/article.asp?issn=2249-4472;year=2024;volume=14;issue=1;spage=73;epage=75;aulast=Vijayan
work_keys_str_mv AT vijayanthivijayan acaseoftrueallergytoamidelocalanestheticsinaparturient
AT adethengunasekaran acaseoftrueallergytoamidelocalanestheticsinaparturient
AT sakthirajanpaneerselvam acaseoftrueallergytoamidelocalanestheticsinaparturient
AT kirthihagovindaraj acaseoftrueallergytoamidelocalanestheticsinaparturient
AT vijayanthivijayan caseoftrueallergytoamidelocalanestheticsinaparturient
AT adethengunasekaran caseoftrueallergytoamidelocalanestheticsinaparturient
AT sakthirajanpaneerselvam caseoftrueallergytoamidelocalanestheticsinaparturient
AT kirthihagovindaraj caseoftrueallergytoamidelocalanestheticsinaparturient