The Janus Face of PAMAM Dendrimers Used to Potentially Cure Nonenzymatic Modifications of Biomacromolecules in Metabolic Disorders—A Critical Review of the Pros and Cons

The Janus Face of PAMAM Dendrimers Used to Potentially Cure Nonenzymatic Modifications of Biomacromolecules in Metabolic Disorders—A Critical Review of the Pros and Cons

Diabetes mellitus, which is characterised by high blood glucose levels and the burden of various macrovascular and microvascular complications, is a cause of much human suffering across the globe. While the use of exogenous insulin and other medications can control and sometimes prevent various diab...

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Bibliographic Details
Main Authors: Cezary Watala, Kamil Karolczak, Karolina Siewiera, Magdalena Labieniec-Watala
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Molecules
Subjects:
PAMAM dendrimers
diabetes mellitus
hyperglycaemia
mitochondria function
bioenergetics
non-enzymatic glycosylation
diabetic markers
in vivo study
Online Access:http://www.mdpi.com/1420-3049/18/11/13769

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