Absorption, Distribution, Metabolism, and Excretion of [<sup>14</sup>C]BS1801, a Selenium-Containing Drug Candidate, in Rats

Absorption, Distribution, Metabolism, and Excretion of [<sup>14</sup>C]BS1801, a Selenium-Containing Drug Candidate, in Rats

BS1801 is a selenium-containing drug candidate with potential for treating liver and lung fibrosis. To fully elucidate the biotransformation of BS1801 in animals and provide sufficient preclinical drug metabolism data for human mass balance study, the metabolism of BS1801 in rats was investigated. W...

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Bibliographic Details
Main Authors: Cheng Yang, Mingzhen Xue, Yifei He, Hanwei Yin, Chen Yang, Dafang Zhong, Huihui Zeng, Yuandong Zheng, Xingxing Diao
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Molecules
Subjects:
[<sup>14</sup>C]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Online Access:https://www.mdpi.com/1420-3049/28/24/8102

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