Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning

Introduction: Delayed treatment of ethylene glycol poisoning can have catastrophic consequences that may result in death. Case report: Three young men presented to the Emergency Centre (EC) with a main complaint of feeling unwell after consuming “homemade alcohol”. A fourth person had died at home a...

Full description

Bibliographic Details
Main Authors: A.E. Laher, L.N. Goldstein, M.D. Wells, N. Dufourq, P. Moodley
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:African Journal of Emergency Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211419X12001218
_version_ 1818364906884300800
author A.E. Laher
L.N. Goldstein
M.D. Wells
N. Dufourq
P. Moodley
author_facet A.E. Laher
L.N. Goldstein
M.D. Wells
N. Dufourq
P. Moodley
author_sort A.E. Laher
collection DOAJ
description Introduction: Delayed treatment of ethylene glycol poisoning can have catastrophic consequences that may result in death. Case report: Three young men presented to the Emergency Centre (EC) with a main complaint of feeling unwell after consuming “homemade alcohol”. A fourth person had died at home an hour earlier. Blood analysis revealed a raised anion gap metabolic acidosis as well as a raised osmolar gap in all three patients. Discussion: The clinical presentation of ethylene glycol and methanol poisoning is non-specific and can be difficult to differentiate from ethanol intoxication. Homemade alcohol preparations are commonly adulterated with ethylene glycol and methanol to improve their taste and sting. Toxic alcohol analysis is not routinely carried out by most laboratory services in South Africa, and when carried out, results are only made available a few days later. A high index of suspicion coupled with early blood gas analysis and a need for prompt and effective treatment whilst awaiting toxicology analysis may limit the associated high morbidity and mortality.
first_indexed 2024-12-13T22:11:49Z
format Article
id doaj.art-32263eccc1b24b9cb4c07210713dbb5d
institution Directory Open Access Journal
issn 2211-419X
language English
last_indexed 2024-12-13T22:11:49Z
publishDate 2013-06-01
publisher Elsevier
record_format Article
series African Journal of Emergency Medicine
spelling doaj.art-32263eccc1b24b9cb4c07210713dbb5d2022-12-21T23:29:41ZengElsevierAfrican Journal of Emergency Medicine2211-419X2013-06-0132717410.1016/j.afjem.2012.10.002Unwell after drinking homemade alcohol – A case of ethylene glycol poisoningA.E. LaherL.N. GoldsteinM.D. WellsN. DufourqP. MoodleyIntroduction: Delayed treatment of ethylene glycol poisoning can have catastrophic consequences that may result in death. Case report: Three young men presented to the Emergency Centre (EC) with a main complaint of feeling unwell after consuming “homemade alcohol”. A fourth person had died at home an hour earlier. Blood analysis revealed a raised anion gap metabolic acidosis as well as a raised osmolar gap in all three patients. Discussion: The clinical presentation of ethylene glycol and methanol poisoning is non-specific and can be difficult to differentiate from ethanol intoxication. Homemade alcohol preparations are commonly adulterated with ethylene glycol and methanol to improve their taste and sting. Toxic alcohol analysis is not routinely carried out by most laboratory services in South Africa, and when carried out, results are only made available a few days later. A high index of suspicion coupled with early blood gas analysis and a need for prompt and effective treatment whilst awaiting toxicology analysis may limit the associated high morbidity and mortality.http://www.sciencedirect.com/science/article/pii/S2211419X12001218Homemade alcoholEthylene glycol poisoningRaised anion gap metabolic acidosisRaised osmolar gapHigh index of suspicion
spellingShingle A.E. Laher
L.N. Goldstein
M.D. Wells
N. Dufourq
P. Moodley
Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
African Journal of Emergency Medicine
Homemade alcohol
Ethylene glycol poisoning
Raised anion gap metabolic acidosis
Raised osmolar gap
High index of suspicion
title Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
title_full Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
title_fullStr Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
title_full_unstemmed Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
title_short Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning
title_sort unwell after drinking homemade alcohol a case of ethylene glycol poisoning
topic Homemade alcohol
Ethylene glycol poisoning
Raised anion gap metabolic acidosis
Raised osmolar gap
High index of suspicion
url http://www.sciencedirect.com/science/article/pii/S2211419X12001218
work_keys_str_mv AT aelaher unwellafterdrinkinghomemadealcoholacaseofethyleneglycolpoisoning
AT lngoldstein unwellafterdrinkinghomemadealcoholacaseofethyleneglycolpoisoning
AT mdwells unwellafterdrinkinghomemadealcoholacaseofethyleneglycolpoisoning
AT ndufourq unwellafterdrinkinghomemadealcoholacaseofethyleneglycolpoisoning
AT pmoodley unwellafterdrinkinghomemadealcoholacaseofethyleneglycolpoisoning