RNA sequencing reveals a slow to fast muscle fiber type transition after olanzapine infusion in rats.

RNA sequencing reveals a slow to fast muscle fiber type transition after olanzapine infusion in rats.

Second generation antipsychotics (SGAs), like olanzapine, exhibit acute metabolic side effects leading to metabolic inflexibility, hyperglycemia, adiposity and diabetes. Understanding how SGAs affect the skeletal muscle transcriptome could elucidate approaches for mitigating these side effects. Male...

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Bibliographic Details
Main Authors: Christopher J Lynch, Yuping Xu, Andras Hajnal, Anna C Salzberg, Yuka Imamura Kawasawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4404103?pdf=render

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