Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy
Objective: To explore the diagnostic value of cardiac magnetic resonance feature tracking (CMR-FT) divided left atrial (LA) strain in differentiating constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). Methods: Patients with CP (n = 40) and RCM (n = 40), and another 40 normal contro...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024047996 |
| _version_ | 1827292705540014080 |
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| author | Kairui Bo Yichen Zhao Xuelian Gao Yanchun Chen Yue Ren Yifeng Gao Zhen Zhou Hui Wang Lei Xu |
| author_facet | Kairui Bo Yichen Zhao Xuelian Gao Yanchun Chen Yue Ren Yifeng Gao Zhen Zhou Hui Wang Lei Xu |
| author_sort | Kairui Bo |
| collection | DOAJ |
| description | Objective: To explore the diagnostic value of cardiac magnetic resonance feature tracking (CMR-FT) divided left atrial (LA) strain in differentiating constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). Methods: Patients with CP (n = 40) and RCM (n = 40), and another 40 normal control group were retrospectively enrolled over a period of 8 years at a tertiary cardiac centre. Left ventricular (LV) and biatrial strain and strain rate (SR) were measured. Atrial strain was used to differentiate between patients with CP and RCM. Then, patients were grouped according to their left ventricular ejection fraction (LVEF), either ≥50% or < 50%. A deeper analysis was done to evaluate the diagnostic value of atrial strain in these subgroups. Receiver operating characteristic curves (ROC) were used to assess the accuracy of myocardial strain based on CMR FT for the differential diagnosis of CP and RCM. Results: LV and LA strain and SR were significantly lower in patients with CP and RCM than those in the normal controls (P < 0.05). LA strain and SR were significantly lower in the RCM group than in the CP group (P < 0.05). In patients with either LVEF≥50% or＜50%, LA strain were lower in the RCM group than in the CP group (P < 0.05). ROC analysis showed that LA stored strain (LA-εs) had a good differential diagnostic value for CP and RCM, with an area under the curve (AUC) of 0.811 and an optimal cutoff value of 6.98%, above this value it tends to develop CP. Further, an excellent differential diagnostic value was found in patients with LVEF＜50%, with an AUC of 0.955. Conclusion: LA strain analysis obtained by CMR-FT provides good differential diagnostic value for distinguishing CP from RCM, especially in patients with LVEF＜50%. |
| first_indexed | 2024-04-24T13:10:24Z |
| format | Article |
| id | doaj.art-322cac4907db4f77951e1a6001c1add8 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:10:24Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-322cac4907db4f77951e1a6001c1add82024-04-05T04:41:11ZengElsevierHeliyon2405-84402024-04-01107e28768Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathyKairui Bo0Yichen Zhao1Xuelian Gao2Yanchun Chen3Yue Ren4Yifeng Gao5Zhen Zhou6Hui Wang7Lei Xu8Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, ChinaDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China; Corresponding author. Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, No. 2 Anzhen Rd, Chaoyang District, Beijing, 100029, China.Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China; Corresponding author. Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, No. 2 Anzhen Rd, Chaoyang District, Beijing, 100029, China.Objective: To explore the diagnostic value of cardiac magnetic resonance feature tracking (CMR-FT) divided left atrial (LA) strain in differentiating constrictive pericarditis (CP) and restrictive cardiomyopathy (RCM). Methods: Patients with CP (n = 40) and RCM (n = 40), and another 40 normal control group were retrospectively enrolled over a period of 8 years at a tertiary cardiac centre. Left ventricular (LV) and biatrial strain and strain rate (SR) were measured. Atrial strain was used to differentiate between patients with CP and RCM. Then, patients were grouped according to their left ventricular ejection fraction (LVEF), either ≥50% or < 50%. A deeper analysis was done to evaluate the diagnostic value of atrial strain in these subgroups. Receiver operating characteristic curves (ROC) were used to assess the accuracy of myocardial strain based on CMR FT for the differential diagnosis of CP and RCM. Results: LV and LA strain and SR were significantly lower in patients with CP and RCM than those in the normal controls (P < 0.05). LA strain and SR were significantly lower in the RCM group than in the CP group (P < 0.05). In patients with either LVEF≥50% or＜50%, LA strain were lower in the RCM group than in the CP group (P < 0.05). ROC analysis showed that LA stored strain (LA-εs) had a good differential diagnostic value for CP and RCM, with an area under the curve (AUC) of 0.811 and an optimal cutoff value of 6.98%, above this value it tends to develop CP. Further, an excellent differential diagnostic value was found in patients with LVEF＜50%, with an AUC of 0.955. Conclusion: LA strain analysis obtained by CMR-FT provides good differential diagnostic value for distinguishing CP from RCM, especially in patients with LVEF＜50%.http://www.sciencedirect.com/science/article/pii/S2405844024047996Constrictive pericarditisRestrictive cardiomyopathyLeft atriumMyocardial strain |
| spellingShingle | Kairui Bo Yichen Zhao Xuelian Gao Yanchun Chen Yue Ren Yifeng Gao Zhen Zhou Hui Wang Lei Xu Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy Heliyon Constrictive pericarditis Restrictive cardiomyopathy Left atrium Myocardial strain |
| title | Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| title_full | Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| title_fullStr | Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| title_full_unstemmed | Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| title_short | Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| title_sort | cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy |
| topic | Constrictive pericarditis Restrictive cardiomyopathy Left atrium Myocardial strain |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024047996 |
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