Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives
Electrochemical biosensing devices are known for their simple operational procedures, low fabrication cost, and suitable real-time detection. Despite these advantages, they have shown some limitations in the immobilization of biochemicals. The development of alternative materials to overcome these d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/13/1/142 |
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| author | Samuel Chagas de Assis Daniella Lury Morgado Desiree Tamara Scheidt Samara Silva de Souza Marco Roberto Cavallari Oswaldo Hideo Ando Junior Emanuel Carrilho |
| author_facet | Samuel Chagas de Assis Daniella Lury Morgado Desiree Tamara Scheidt Samara Silva de Souza Marco Roberto Cavallari Oswaldo Hideo Ando Junior Emanuel Carrilho |
| author_sort | Samuel Chagas de Assis |
| collection | DOAJ |
| description | Electrochemical biosensing devices are known for their simple operational procedures, low fabrication cost, and suitable real-time detection. Despite these advantages, they have shown some limitations in the immobilization of biochemicals. The development of alternative materials to overcome these drawbacks has attracted significant attention. Nanocellulose-based materials have revealed valuable features due to their capacity for the immobilization of biomolecules, structural flexibility, and biocompatibility. Bacterial nanocellulose (BNC) has gained a promising role as an alternative to antifouling surfaces. To widen its applicability as a biosensing device, BNC may form part of the supports for the immobilization of specific materials. The possibilities of modification methods and in situ and ex situ functionalization enable new BNC properties. With the new insights into nanoscale studies, we expect that many biosensors currently based on plastic, glass, or paper platforms will rely on renewable platforms, especially BNC ones. Moreover, substrates based on BNC seem to have paved the way for the development of sensing platforms with minimally invasive approaches, such as wearable devices, due to their mechanical flexibility and biocompatibility. |
| first_indexed | 2024-03-09T13:24:07Z |
| format | Article |
| id | doaj.art-322f20e67baa4c4db4f91900f766b53f |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T13:24:07Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-322f20e67baa4c4db4f91900f766b53f2023-11-30T21:26:07ZengMDPI AGBiosensors2079-63742023-01-0113114210.3390/bios13010142Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future PerspectivesSamuel Chagas de Assis0Daniella Lury Morgado1Desiree Tamara Scheidt2Samara Silva de Souza3Marco Roberto Cavallari4Oswaldo Hideo Ando Junior5Emanuel Carrilho6Grupo de Pesquisa em Energia e Sustentabilidade Energética-GPEnSE, Universidade Federal da Integração Latino-Americana—UNILA, Av. Sílvio Américo Sasdelli, 1842, Foz do Iguaçu 85866-000, PR, BrazilGrupo de Pesquisa em Energia e Sustentabilidade Energética-GPEnSE, Universidade Federal da Integração Latino-Americana—UNILA, Av. Sílvio Américo Sasdelli, 1842, Foz do Iguaçu 85866-000, PR, BrazilInstituto de Química de São Carlos, Universidade de São Paulo, São Carlos 13566-590, SP, BrazilGrupo de Pesquisa em Energia e Sustentabilidade Energética-GPEnSE, Universidade Federal da Integração Latino-Americana—UNILA, Av. Sílvio Américo Sasdelli, 1842, Foz do Iguaçu 85866-000, PR, BrazilSchool of Electrical and Computer Engineering, University of Campinas (Unicamp), Av. Albert Einstein 400, Campinas 13083-852, SP, BrazilGrupo de Pesquisa em Energia e Sustentabilidade Energética-GPEnSE, Universidade Federal da Integração Latino-Americana—UNILA, Av. Sílvio Américo Sasdelli, 1842, Foz do Iguaçu 85866-000, PR, BrazilInstituto de Química de São Carlos, Universidade de São Paulo, São Carlos 13566-590, SP, BrazilElectrochemical biosensing devices are known for their simple operational procedures, low fabrication cost, and suitable real-time detection. Despite these advantages, they have shown some limitations in the immobilization of biochemicals. The development of alternative materials to overcome these drawbacks has attracted significant attention. Nanocellulose-based materials have revealed valuable features due to their capacity for the immobilization of biomolecules, structural flexibility, and biocompatibility. Bacterial nanocellulose (BNC) has gained a promising role as an alternative to antifouling surfaces. To widen its applicability as a biosensing device, BNC may form part of the supports for the immobilization of specific materials. The possibilities of modification methods and in situ and ex situ functionalization enable new BNC properties. With the new insights into nanoscale studies, we expect that many biosensors currently based on plastic, glass, or paper platforms will rely on renewable platforms, especially BNC ones. Moreover, substrates based on BNC seem to have paved the way for the development of sensing platforms with minimally invasive approaches, such as wearable devices, due to their mechanical flexibility and biocompatibility.https://www.mdpi.com/2079-6374/13/1/142bacterial nanocellulosebiosensorsex situfunctionalizationin situ |
| spellingShingle | Samuel Chagas de Assis Daniella Lury Morgado Desiree Tamara Scheidt Samara Silva de Souza Marco Roberto Cavallari Oswaldo Hideo Ando Junior Emanuel Carrilho Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives Biosensors bacterial nanocellulose biosensors ex situ functionalization in situ |
| title | Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives |
| title_full | Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives |
| title_fullStr | Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives |
| title_full_unstemmed | Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives |
| title_short | Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives |
| title_sort | review of bacterial nanocellulose based electrochemical biosensors functionalization challenges and future perspectives |
| topic | bacterial nanocellulose biosensors ex situ functionalization in situ |
| url | https://www.mdpi.com/2079-6374/13/1/142 |
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