Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon

The diagnosis of multiple primary malignancy (MPM) is not uncommon. Nevertheless synchronous MPM involving urinary bladder and hypopharynx is an extremely unusual event.No such cases have been reported so far in English literature to our review. We report the case of 62-year-old male patient who pre...

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Main Authors: Kuna J, Das P, Patnayak R, Tyagi A
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-04-01
Series:Journal of Clinical and Scientific Research
Subjects:
Online Access:http://svimstpt.ap.nic.in/jcsr/apr-jun16_files/4cr16.pdf
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author Kuna J
Das P
Patnayak R
Tyagi A
author_facet Kuna J
Das P
Patnayak R
Tyagi A
author_sort Kuna J
collection DOAJ
description The diagnosis of multiple primary malignancy (MPM) is not uncommon. Nevertheless synchronous MPM involving urinary bladder and hypopharynx is an extremely unusual event.No such cases have been reported so far in English literature to our review. We report the case of 62-year-old male patient who presented with haematuria and later dysphagia to solids. Whole body 18F-fluro deoxy glucose positron emission tomography- computed tomography (18FFDG PET-CT) revealed two distinct lesions one in hypopharynx and another in urinary bladder. Biopsy from the urinary bladder mass and the hypopharyngeal lesion were suggestive of urothelial carcinoma and poorly differentiated squamous cell carcinoma respectively. The patient was treated with concurrent chemo-radiotherapy to hypopharynx. Following treatment he had improvement of dysphagia. Haematuria had also stopped. Because of severe comorbidities the planned radical cystectomy or radiotherapy were deferred. Currently the patient is in symptomatic remission six months following treatment.
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spelling doaj.art-3231caea6ab64183a47617ca47078dfa2022-12-22T04:06:07ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572016-04-0152136139http://dx.doi.org/10.15380/2277-5706.JCSR.15.014Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenonKuna J0Das P1Patnayak R2Tyagi A3Sri Venkateswara Institute of Medical Sciences, TirupatiSri Venkateswara Institute of Medical Sciences, TirupatiSri Venkateswara Institute of Medical Sciences, TirupatiSri Venkateswara Institute of Medical Sciences, TirupatiThe diagnosis of multiple primary malignancy (MPM) is not uncommon. Nevertheless synchronous MPM involving urinary bladder and hypopharynx is an extremely unusual event.No such cases have been reported so far in English literature to our review. We report the case of 62-year-old male patient who presented with haematuria and later dysphagia to solids. Whole body 18F-fluro deoxy glucose positron emission tomography- computed tomography (18FFDG PET-CT) revealed two distinct lesions one in hypopharynx and another in urinary bladder. Biopsy from the urinary bladder mass and the hypopharyngeal lesion were suggestive of urothelial carcinoma and poorly differentiated squamous cell carcinoma respectively. The patient was treated with concurrent chemo-radiotherapy to hypopharynx. Following treatment he had improvement of dysphagia. Haematuria had also stopped. Because of severe comorbidities the planned radical cystectomy or radiotherapy were deferred. Currently the patient is in symptomatic remission six months following treatment.http://svimstpt.ap.nic.in/jcsr/apr-jun16_files/4cr16.pdfSynchronousDual primary malignancyHypopharynxUrinary bladder
spellingShingle Kuna J
Das P
Patnayak R
Tyagi A
Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
Journal of Clinical and Scientific Research
Synchronous
Dual primary malignancy
Hypopharynx
Urinary bladder
title Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
title_full Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
title_fullStr Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
title_full_unstemmed Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
title_short Synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62-year-old male patient: An extremely rare phenomenon
title_sort synchronous dual primary malignancy of urinary bladder and hypopharynx in a 62 year old male patient an extremely rare phenomenon
topic Synchronous
Dual primary malignancy
Hypopharynx
Urinary bladder
url http://svimstpt.ap.nic.in/jcsr/apr-jun16_files/4cr16.pdf
work_keys_str_mv AT kunaj synchronousdualprimarymalignancyofurinarybladderandhypopharynxina62yearoldmalepatientanextremelyrarephenomenon
AT dasp synchronousdualprimarymalignancyofurinarybladderandhypopharynxina62yearoldmalepatientanextremelyrarephenomenon
AT patnayakr synchronousdualprimarymalignancyofurinarybladderandhypopharynxina62yearoldmalepatientanextremelyrarephenomenon
AT tyagia synchronousdualprimarymalignancyofurinarybladderandhypopharynxina62yearoldmalepatientanextremelyrarephenomenon