Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy
Patients with diffused Systemic Sclerosis (dSSc) are more subject to severe respiratory complications with higher rates of intensive care unit (ICU) admission. Vaccination represents the most effective means of prevention and care for frail patients, such as SSc patients, preventing infections, redu...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-01-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2025732 |
| _version_ | 1797673227018829824 |
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| author | Giuseppe Murdaca Giovanni Noberasco Dario Olobardi Matilde Ogliastro Raffaella Sibilio Giacomo Sambuceti Riccardo Balzano Laura Sticchi Giancarlo Icardi Andrea Orsi |
| author_facet | Giuseppe Murdaca Giovanni Noberasco Dario Olobardi Matilde Ogliastro Raffaella Sibilio Giacomo Sambuceti Riccardo Balzano Laura Sticchi Giancarlo Icardi Andrea Orsi |
| author_sort | Giuseppe Murdaca |
| collection | DOAJ |
| description | Patients with diffused Systemic Sclerosis (dSSc) are more subject to severe respiratory complications with higher rates of intensive care unit (ICU) admission. Vaccination represents the most effective means of prevention and care for frail patients, such as SSc patients, preventing infections, reducing mortality and morbidity, and granting a better quality of life. Both vaccinations against seasonal influenza and Streptococcus pneumoniae are currently recommended by the European League Against Rheumatism (EULAR) guidelines on vaccination. The aim of this study is to give an updated analysis on S. pneumoniae and seasonal influenza vaccination coverage in a cohort of 91 patients with SSc and to investigate demographic and clinical variables significantly related to vaccine acceptance. The correlation between vaccine administration and other factors was investigated using a binomial logistic regression to evaluate the adjusted odds ratio (aOR). The patients followed up in this study reached higher percentages than the general population, passing the 75% target for both influenza and anti-pneumococcal vaccinations and reaching for influenza vaccine coverage rates of 83.8% for subjects undergoing immunosuppressive therapies and 88.9% for elderly subjects. For the latter group, it is important to emphasize the strong correlation between older age groups and vaccination acceptance. |
| first_indexed | 2024-03-11T21:41:28Z |
| format | Article |
| id | doaj.art-3236ca32ef5446b19cd5a2b2abc33121 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:41:28Z |
| publishDate | 2022-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-3236ca32ef5446b19cd5a2b2abc331212023-09-26T12:55:44ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-01-0118110.1080/21645515.2022.20257322025732Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest ItalyGiuseppe Murdaca0Giovanni Noberasco1Dario Olobardi2Matilde Ogliastro3Raffaella Sibilio4Giacomo Sambuceti5Riccardo Balzano6Laura Sticchi7Giancarlo Icardi8Andrea Orsi9University of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaUniversity of GenovaPatients with diffused Systemic Sclerosis (dSSc) are more subject to severe respiratory complications with higher rates of intensive care unit (ICU) admission. Vaccination represents the most effective means of prevention and care for frail patients, such as SSc patients, preventing infections, reducing mortality and morbidity, and granting a better quality of life. Both vaccinations against seasonal influenza and Streptococcus pneumoniae are currently recommended by the European League Against Rheumatism (EULAR) guidelines on vaccination. The aim of this study is to give an updated analysis on S. pneumoniae and seasonal influenza vaccination coverage in a cohort of 91 patients with SSc and to investigate demographic and clinical variables significantly related to vaccine acceptance. The correlation between vaccine administration and other factors was investigated using a binomial logistic regression to evaluate the adjusted odds ratio (aOR). The patients followed up in this study reached higher percentages than the general population, passing the 75% target for both influenza and anti-pneumococcal vaccinations and reaching for influenza vaccine coverage rates of 83.8% for subjects undergoing immunosuppressive therapies and 88.9% for elderly subjects. For the latter group, it is important to emphasize the strong correlation between older age groups and vaccination acceptance.http://dx.doi.org/10.1080/21645515.2022.2025732systemic sclerosisvaccinesfluinfluenzapneumonias. pneumoniae |
| spellingShingle | Giuseppe Murdaca Giovanni Noberasco Dario Olobardi Matilde Ogliastro Raffaella Sibilio Giacomo Sambuceti Riccardo Balzano Laura Sticchi Giancarlo Icardi Andrea Orsi Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy Human Vaccines & Immunotherapeutics systemic sclerosis vaccines flu influenza pneumonia s. pneumoniae |
| title | Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy |
| title_full | Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy |
| title_fullStr | Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy |
| title_full_unstemmed | Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy |
| title_short | Systemic sclerosis and vaccinations: a three-year register-based cohort study about vaccination rate and uptake from Liguria referral center, northwest Italy |
| title_sort | systemic sclerosis and vaccinations a three year register based cohort study about vaccination rate and uptake from liguria referral center northwest italy |
| topic | systemic sclerosis vaccines flu influenza pneumonia s. pneumoniae |
| url | http://dx.doi.org/10.1080/21645515.2022.2025732 |
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