Protective effect of Nigella sativa oil against thioacetamide-induced liver injury in rats

antioxidant which is known to have liver protective effects, against thioacetamide (TAA)-induced liver injury. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, thioacetamide, compared the NSO and NAC liver preventive effects in experimental animal model. Wistar-albino rats w...

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Bibliographic Details
Main Authors: Kevser Tanbek, Elif Ozerol, Sedat Bilgic, Mustafa Iraz, Nurhan Sahin, Cemil Colak
Format: Article
Language:English
Published: Society of Turaz Bilim 2017-03-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=229294
Description
Summary:antioxidant which is known to have liver protective effects, against thioacetamide (TAA)-induced liver injury. Accordingly, we aimed to investigate the toxicity of a hepatotoxic agent, thioacetamide, compared the NSO and NAC liver preventive effects in experimental animal model. Wistar-albino rats were randomly allocated to five groups, each consisting of eight rats, and were subjected to different treatment regimens for 6 days. Alanine aminotransferase (ALT), malondialdehyde (MDA), and protein carbonyl (PC) levels decreased significantly by NSO treatment (P [Med-Science 2017; 6(1.000): 96-103]
ISSN:2147-0634