Mast cells are at the interface between the external environment and the inner organism
Mast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and cleara...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2024-01-01
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Series: | Frontiers in Medicine |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/full |
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author | Domenico Ribatti |
author_facet | Domenico Ribatti |
author_sort | Domenico Ribatti |
collection | DOAJ |
description | Mast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and clearance of microbial pathogens. This mini-review article discusses the role of mast cells in these barrier systems. |
first_indexed | 2024-03-08T17:05:42Z |
format | Article |
id | doaj.art-3239fc3cf96f4d6a87761b8352975143 |
institution | Directory Open Access Journal |
issn | 2296-858X |
language | English |
last_indexed | 2024-03-08T17:05:42Z |
publishDate | 2024-01-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Medicine |
spelling | doaj.art-3239fc3cf96f4d6a87761b83529751432024-01-04T04:55:30ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-01-011010.3389/fmed.2023.13320471332047Mast cells are at the interface between the external environment and the inner organismDomenico RibattiMast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and clearance of microbial pathogens. This mini-review article discusses the role of mast cells in these barrier systems.https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/fullmast cellsgastrointestinal tractlungskinbarrier system |
spellingShingle | Domenico Ribatti Mast cells are at the interface between the external environment and the inner organism Frontiers in Medicine mast cells gastrointestinal tract lung skin barrier system |
title | Mast cells are at the interface between the external environment and the inner organism |
title_full | Mast cells are at the interface between the external environment and the inner organism |
title_fullStr | Mast cells are at the interface between the external environment and the inner organism |
title_full_unstemmed | Mast cells are at the interface between the external environment and the inner organism |
title_short | Mast cells are at the interface between the external environment and the inner organism |
title_sort | mast cells are at the interface between the external environment and the inner organism |
topic | mast cells gastrointestinal tract lung skin barrier system |
url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/full |
work_keys_str_mv | AT domenicoribatti mastcellsareattheinterfacebetweentheexternalenvironmentandtheinnerorganism |