Mast cells are at the interface between the external environment and the inner organism

Mast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and cleara...

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Main Author: Domenico Ribatti
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/full
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author Domenico Ribatti
author_facet Domenico Ribatti
author_sort Domenico Ribatti
collection DOAJ
description Mast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and clearance of microbial pathogens. This mini-review article discusses the role of mast cells in these barrier systems.
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spelling doaj.art-3239fc3cf96f4d6a87761b83529751432024-01-04T04:55:30ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-01-011010.3389/fmed.2023.13320471332047Mast cells are at the interface between the external environment and the inner organismDomenico RibattiMast cells localized at the level of the mucosal barrier in the skin, lung, and gastrointestinal tract, intervene in the modulation of the function of the epithelial cells and are involved in innate and adaptive defensive responses. In this context, mast cells intervene in the recognition and clearance of microbial pathogens. This mini-review article discusses the role of mast cells in these barrier systems.https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/fullmast cellsgastrointestinal tractlungskinbarrier system
spellingShingle Domenico Ribatti
Mast cells are at the interface between the external environment and the inner organism
Frontiers in Medicine
mast cells
gastrointestinal tract
lung
skin
barrier system
title Mast cells are at the interface between the external environment and the inner organism
title_full Mast cells are at the interface between the external environment and the inner organism
title_fullStr Mast cells are at the interface between the external environment and the inner organism
title_full_unstemmed Mast cells are at the interface between the external environment and the inner organism
title_short Mast cells are at the interface between the external environment and the inner organism
title_sort mast cells are at the interface between the external environment and the inner organism
topic mast cells
gastrointestinal tract
lung
skin
barrier system
url https://www.frontiersin.org/articles/10.3389/fmed.2023.1332047/full
work_keys_str_mv AT domenicoribatti mastcellsareattheinterfacebetweentheexternalenvironmentandtheinnerorganism