Transcriptomic Analysis of Persistent Infection with Foot-and-Mouth Disease Virus in Cattle Suggests Impairment of Apoptosis and Cell-Mediated Immunity in the Nasopharynx.

In order to investigate the mechanisms of persistent foot-and-mouth disease virus (FMDV) infection in cattle, transcriptome alterations associated with the FMDV carrier state were characterized using a bovine whole-transcriptome microarray. Eighteen cattle (8 vaccinated with a recombinant FMDV A vac...

Description complète

Détails bibliographiques
Auteurs principaux: Michael Eschbaumer, Carolina Stenfeldt, George R Smoliga, Juan M Pacheco, Luis L Rodriguez, Robert W Li, James Zhu, Jonathan Arzt
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2016-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC5028045?pdf=render