BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer’s Disease Pathology

BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer’s Disease Pathology

Alzheimer’s disease (AD) is a fatal progressive neurodegenerative disorder characterized by increasing loss in memory, cognition, and function of daily living. Among the many pathologic events observed in the progression of AD, changes in amyloid β peptide (Aβ) metabolism proceed fastest, and preced...

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Bibliographic Details
Main Author:	Gerald Koelsch
Format:	Article
Language:	English
Published:	MDPI AG 2017-10-01
Series:	Molecules
Subjects:	Alzheimer’s disease amyloid hypothesis BACE1 beta secretase pharmacology
Online Access:	https://www.mdpi.com/1420-3049/22/10/1723

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