Mediating the death of dormant tumor cells

Mediating the death of dormant tumor cells

How immunological cues trigger cancer cell-intrinsic signaling pathways for their entering dormancy remains an enigma. In out recent studies, we found that IFN-β induces tumor-repopulating cells (TRC) into dormancy by activating Indoleamine-pyrrole 2,3-dioxygenase (IDO)-Kynurenine-aryl hydrocarbon r...

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Bibliographic Details
Main Authors: Yuying Liu, Jiadi Lv, Bo Huang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Molecular & Cellular Oncology
Subjects:
tumor-repopulating cells
tumor dormancy
immune cytokine
indoleamine-pyrrole 2,3-dioxygenase
kynurenine
aryl hydrocarbon receptor
Online Access:http://dx.doi.org/10.1080/23723556.2018.1458013

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