Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil

Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil

ABSTRACT Background: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. Methods: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. Result...

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Bibliographic Details
Main Authors: Evelyn Cristine da Silva, Felipe Fornazari, João Marcelo Azevedo de Paula Antunes, Larissa de Castro Demoner, Lucia Helena O’Dwyer de Oliveira, Marina Gea Peres, Jane Megid, Helio Langoni
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2023-09-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
leptospirosis
qPCR
Wildlife
Renal carrier
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822023000100614&tlng=en
Description
Summary:ABSTRACT Background: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. Methods: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. Results: Thirty-five animals (21.34%) tested positive, including five rodent species: Akodon montensis (2/21; 9.5%), Necromys lasiurus (1/4; 25%), Oligoryzomys nigripes (24/92; 26.1%), Oligoryzomys flavescens (5/26; 19.2%), and Sooretamys angouya (3/14; 21.4%). Botucatu municipality exhibited the highest prevalence, with 42.5% (20/47) of the animals testing positive. Conclusions: The presence of Leptospira spp. in wild rodents suggests they may be chronic carriers, contaminating the environment.
ISSN:1678-9849

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