Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells

Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells

DNA methylation is one of a number of modes of epigenetic gene regulation. Here, we profile the DNA methylome, transcriptome, and global occupancy of histone modifications (H3K4me1, H3K4me3, H3K27me3, and H3K27ac) in a series of mouse embryonic stem cells (mESCs) with varying DNA methylation levels...

Full description

Bibliographic Details
Main Authors:	Andrew D. King, Kevin Huang, Liudmilla Rubbi, Shuo Liu, Cun-Yu Wang, Yinsheng Wang, Matteo Pellegrini, Guoping Fan
Format:	Article
Language:	English
Published:	Elsevier 2016-09-01
Series:	Cell Reports
Subjects:	DNA methylation histone modifications chromatin polycomb embryonic stem cells enhancers promoters gene regulation epigenetics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124716311792

Similar Items

Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
by: Cheng Dong, et al.
Published: (2020-09-01)

Histone modifications in neurodifferentiation of embryonic stem cells
by: Min Huang, et al.
Published: (2022-01-01)

Coordinate activation of a target gene by KDM1C histone demethylase and OTLD1 histone deubiquitinase in Arabidopsis
by: Ido Keren, et al.
Published: (2019-06-01)

Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells
by: Donnchadh S. Dunican, et al.
Published: (2020-03-01)

Activation of gene expression by histone deubiquitinase OTLD1
by: Ido Keren, et al.
Published: (2017-07-01)

Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain
by: Sean J. Farley, et al.
Published: (2022-12-01)

Histone Modifications and Other Facets of Epigenetic Regulation in Trypanosomatids: Leaving Their Mark
by: Swati Saha
Published: (2020-10-01)

Histone variants and modifications during abiotic stress response
by: Rocío Nunez-Vazquez, et al.
Published: (2022-12-01)

Structural Paradigms in the Recognition of the Nucleosome Core Particle by Histone Lysine Methyltransferases
by: Ashley Janna, et al.
Published: (2020-07-01)

Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer
by: Joyce Taylor-Papadimitriou, et al.
Published: (2022-03-01)

The Dynamics of Histone Modifications during Mammalian Zygotic Genome Activation
by: Francisco Sotomayor-Lugo, et al.
Published: (2024-01-01)

Cold stress induces rapid gene-specific changes in the levels of H3K4me3 and H3K27me3 in Arabidopsis thaliana
by: Léa Faivre, et al.
Published: (2024-04-01)

Histone Methylation and Memory of Environmental Stress
by: Paola Fabrizio, et al.
Published: (2019-04-01)

New Insights into the Role of Histone Changes in Aging
by: Sun-Ju Yi, et al.
Published: (2020-11-01)

No Easy Way Out for EZH2: Its Pleiotropic, Noncanonical Effects on Gene Regulation and Cellular Function
by: Jun Wang, et al.
Published: (2020-12-01)

Editorial: Plant epigenetics and chromatin dynamics - EPIPLANT 2021-2022
by: Guillaume Moissiard, et al.
Published: (2023-11-01)

Mechanisms guiding Polycomb activities during gene silencing in Arabidopsis thaliana
by: Chongsheng eHe, et al.
Published: (2013-11-01)

Controllers of histone methylation-modifying enzymes in gastrointestinal cancers
by: Ling Li, et al.
Published: (2024-05-01)

The Expanding Constellation of Histone Post-Translational Modifications in the Epigenetic Landscape
by: Vincenzo Cavalieri
Published: (2021-10-01)

Chromatin-Based Regulation of Plant Root Development
by: Dong-Hong Chen, et al.
Published: (2018-10-01)

The Impact of Epigenetic Modifications on Adaptive Resistance Evolution in Glioblastoma
by: Qiong Wu, et al.
Published: (2021-08-01)

Concerted Flexibility of Chromatin Structure, Methylome, and Histone Modifications along with Plant Stress Responses
by: Ana Paula Santos, et al.
Published: (2017-01-01)

The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors
by: João Lobo, et al.
Published: (2018-12-01)

Chromatin Structure and Dynamics: Focus on Neuronal Differentiation and Pathological Implication
by: Sophie A. Nothof, et al.
Published: (2022-04-01)

UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons
by: S. Jesse Lopez, et al.
Published: (2017-11-01)

Minireview: Chromatin-based regulation of iron homeostasis in plants
by: Justin Su, et al.
Published: (2022-09-01)

Epigenetic Regulation in Sepsis, Role in Pathophysiology and Therapeutic Perspective
by: Renata Brito Falcão-Holanda, et al.
Published: (2021-07-01)

The Advances in Epigenetics for Cancer Radiotherapy
by: Yuexuan Wang, et al.
Published: (2022-05-01)

Histone content increases in differentiating Embryonic Stem Cells.
by: Theodoros eKarnavas, et al.
Published: (2014-08-01)

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation
by: Shusaku Abe, et al.
Published: (2021-10-01)

Plant Deubiquitinases and Their Role in the Control of Gene Expression Through Modification of Histones
by: Eduardo March, et al.
Published: (2018-01-01)

Histone 3 Lysine 27 Trimethylation Signature in Breast Cancer
by: Lidia Borkiewicz
Published: (2021-11-01)

Editorial: Community series in epigenetic regulation in cardiovascular diseases, volume III
by: Zhihua Wang, et al.
Published: (2024-04-01)

The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine Exchange
by: Lindsay Moritz, et al.
Published: (2022-06-01)

The Effects of Early Prenatal Alcohol Exposure on Epigenome and Embryonic Development
by: Essi Wallén, et al.
Published: (2021-07-01)

Elevated levels of the methyltransferase SETD2 causes transcription and alternative splicing changes resulting in oncogenic phenotypes
by: Saikat Bhattacharya, et al.
Published: (2022-08-01)

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes
by: Yuanxin Xi, et al.
Published: (2018-02-01)

O-GlcNAcylation, an epigenetic mark. Focus on the histone code, TET family proteins and Polycomb group proteins.
by: Vanessa eDehennaut, et al.
Published: (2014-09-01)

Phylogenetic relationship and domain organisation of SET domain proteins of Archaeplastida
by: Supriya Sarma, et al.
Published: (2017-12-01)

Identification of polycomb repressive complex 1 and 2 core components in hexaploid bread wheat
by: Beáta Strejčková, et al.
Published: (2020-10-01)